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《China Modern Doctor》 2016-04
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Clinical evaluation of treatment with traditional Chinese medicine combined with FOLFOX4 regimen for postoperation of colorectal carcinoma

LEI Hailong;Department of Oncology,the People's Hospital of Wuhai City in Inner Mongolia;  
Objective To observe and explore the clinical value of treatment with traditional Chinese medicine combined with FOLFOX4 regimen for postoperation of colorectal carcinoma(CC). Methods A total of 38 patients with CC after the treatment of surgery in our hospital from September 2013 to June 2015 were selected as the observation group in this study, in addition, another 36 cases with CC in our hospital within a year and a half before were selected as the control group. The control group were treated with conventional FOLFOX4 regimen after surgery, while the observation group were treated with traditional Chinese medicine on the basis of the control group. TCM syndrome curative effect,adverse reactions, SF-36 score and survival rate of different period in two groups were recorded for statistical analysis.Results The total rates of TCM syndrome curative effect in the control group and observation group were respectively63.9%(23/36) and 78.9%(30/38)(P0.05); the incidence of bone marrow suppression, gastrointestinal reactions, leukocyte decrease, platelet decrease and liver function abnormalities in the observation group was significantly lower than those in the control group(P0.05); the SF-36 score 6 months after the treatment and the survival rates of 1 year and 3 year after the treatment in the observation group were obviously higher than those in the control group(P0.05). Conclusion Using of traditional Chinese medicine combined with FOLFOX4 regimen after the treatment of surgery has a significant effect and significantly improve the condition and quality of life for the patients with CC, thus it 's worth popularization and application in clinic.
【CateGory Index】: R735.34
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