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《Journal of Apoplexy and Nervous Diseases》 1995-01
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Contents of free radicals with spin trapping in vitro by ESR after reperfusion following ischemia

Feng Jiachun, Rao Mingli,Zhang Shuqin,et al  
In this study, contents of free radicals were determined with spin trapping in vitro by electron spin resonance(ESR) in the five brain regions at 10 minutes for global ischemia and 5 minutes to 5 days after reper fusion following ischemia. The spin trap,alpha -phenyl -t-butyl nitrone(PBN) was used, and two line (1x2)ESR spectrum was obtained when a PBN trapped free radical was analyzed. The results showed that contents of free radical increased at ischemia for 10 minutes and 5 minutes to 12 hours after reperfusion. The contents of free radical after reperfusion were higher than that one at ischemia
【Fund】: 国家自然科学基金资助项目
【CateGory Index】: R743
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