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《Journal of China Prescription Drug》 2017-02
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Primary studies on synthesis of aspirin-g-chitosan derivatives

LIU Yong-shan;LIN Rong-xi;ZHAO Zhen-wen;People’s Hospital of Nanhai Foshan;Foshan University;Third People’s Hospital of Foshan;  
Objective To study the synthesis method of aspirin-g-chitosan derivatives. Methods Under the catalysis of DCC and DMAP, certain amount of aspirin and chitosan were added into the amount of chloroform, reactiing 6 h at 50℃. The products were separated by column chromatography and preparative TLC. Then, TLC, IR, UV were used to characterize the product. Results After analysis of TLC, IR and UV, the obtained product is a single component, and it can be identified as aspirin-g-chitosan amide derivatives. Conclusion Under the condition of appropriate catalyst, taking aspirin and chitosan as raw materials, aspirin-g-chitosan derivatives can be synthesized preliminary by appropriate separation and purification methods.
【Fund】: 佛山市医学类科技攻关项目(2014AB00258)
【CateGory Index】: R914.5
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2 LI Ming-chun,ZHOU Sheng-quan,XIN Mei-hua,SONG Yu-ning,WANG Chao(Engineering Research Center of Environment-Friendly Functional Materials, Ministry of Education,College of Material Science and Engineering, Huaqiao University,Xiamen 361021,China);Synthesis and antibacterial activity of N-alkyl quaternary ammonium chitosan derivatives[J];功能材料;2012-17
3 NI Tian-qing,HU Si-yuan First Teaching Hospital of Tianjin University of TCM,Tianjin 300193,China;Research of pharmacologic action and clinical application of chitin and its derivative chitosan[J];现代药物与临床;2012-03
4 SUN Ning-ling;The new progress of Aspirin in primary prevention of cardiovascular and cerebrovascular diseases in 2011[J];中国实用内科杂志;2012-01
5 Zhou Li,Wu Yiguang,Luo Zhonkuang,Liu Bo,Liao Chuandong,Zhang Nian(College of Chemistry and Chemical Engineering,Shenzhen University,Shenzhen Key Laboratory of Functional polymer,Shenzhen 518060,China);Preparation and Controlled Release Characteristic of Aspirin-loaded Chitosan Microspheres[J];广东化工;2010-02
6 XIONG Yan,WU Xue-wen(College of Chemical Engineering,Xiangtan University,Hunan Xiangtan,411105,China);Study on preparation and in vitro release of the oral colon-specific drug delivery systems based on pH sensitive Chitosan[J];中国医院药学杂志;2009-21
7 ZHANG Liuzhen XU Yujie LIU Min WENG Wanwen DING Wenxiu YANG Zhanshan (School of Radiation Medicine and Public Health, Soochow University, Suzhou 215123, China);Preparation and characterization of chitosan with low molecular weight and high degree of deacetylation[J];辐射研究与辐射工艺学报;2009-03
8 Bai Jiangang and Zhu Weiping(People's Hospital of Chibi, Hubei Province, Chibi 437300);Research Progress of Pharmacological Functions of Aspirin[J];中国药事;2008-10
9 LI Wan-hai1,CHENG Yan-jie2,QI Ai-jiu1,WANG Hong1(1.College of Environmental and Biological Engineering,Jilin Institute of Chemical Technology,Jilin City 132022,China;2.Calcium Carbide Plant,PetroChina Jilin PetroChemical Company,Jilin City 132022,China);Preparation of carboxymethyl chitosan and its application[J];吉林化工学院学报;2008-01
10 ZHANG Yanqing,ZHANG Mingchun,XIE Junbo,QI Wuqin,HAN Shuzhen(Dept. of Pharmaceutical Engineering,Tianjin College of Commerce,Tianjin 300134,China)ZHANG Yanqing(School of Pharmaceutical Sciences,Peking University,Beijing 100083,China);Formula Optimization of Aspirin Chitosan-Sodium Alginate Microcapsules and Drug Releasing Mechanism Study[J];中国药房;2007-04
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2 LI Fang;CHEN Bei;ZHU Feng;ZHANG Hao;LIU Hua-Liang;TAN Zhi;Jiangsu Provincial Center for Disease Control and Prevention;;Determination of 6 kinds of quaternary ammonium salts in disinfectants by high performance liquid chromatography with gradient elution[J];江苏预防医学;2017-06
3 NIE Yanjun;ZHENG Jing;CHEN Zhen;XIE Yuanchao;Shandong Institute for Food and Drug Control;;Application of self-control method in consistency evaluation of dissolution curve of Aspirin Enteric-coated Tablets[J];药学研究;2017-11
4 LIANG Li-mei;LI Si-dong;LI Cheng-peng;HOU Ting-ting;College of Chemistry and Environment,Guangdong Ocean University;;Research Progress on Atibacterial Ativity of Citosan and Its Drivatives[J];广州化工;2017-20
5 QIANG Xi-huai;LI Yu;CUI Lu;LIU Ai-zhen;College of Bioresources Chemical and Materials Engineering,Shaanxi University of Science & Technology;College of Chemistry and Chemical Engineering,Shaanxi University of Science &Technology;;The thermal decomposition mechanism of acrylic resin-carboxymethyl chitosan composite coating[J];陕西科技大学学报;2017-03
6 SONG Bin;LIANG Guiling;LI Qunshan;LUO Di;HUANG Xianhua;Huizhou Hospital of Traditional Chinese Medicine;;Analysis of Clinical Prognosis of Upper Digestive Tract Injury of Patients with Long-time Use of Low-dose Aspirin and Coronary Heart Disease[J];中国医药科学;2017-09
7 ZHANG Jing;ZHANG Xun;LIN Yu;WANG Wei-chen;Department of Pharmacy,People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine;College of Pharmacy,Fujian University of Traditional Chinese Medicine;;Meta-analysis on Chitosan in repair clinical surgery wounds healing[J];药物评价研究;2017-04
8 LIU Yong-shan;LIN Rong-xi;ZHAO Zhen-wen;People’s Hospital of Nanhai Foshan;Foshan University;Third People’s Hospital of Foshan;;Primary studies on synthesis of aspirin-g-chitosan derivatives[J];中国处方药;2017-02
9 Song Bin;Liang Guiling;Li Qunshan;Luo Di;Huang Xianhua;Department of Gastroenterology, Huizhou City Hospital of Traditional Chinese Medicine;;Clinical evaluation of upper gastrointestinal tract injury of serology to patients with coronary heart disease(CHD) with long-term low-dose aspirin using[J];中华临床医师杂志(电子版);2017-03
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 FAN Bing,LIU Cheng-sheng,LIU Han,CHEN Li-yuan(College of Marine Life Science,Ocean University of China,Qingdao 266003,China);Preparation and antibacterial activity determination of chitosan derivatives[J];功能材料;2011-S3
2 LI Mingchun,XU Tao,XIN Meihua(College of Material Science and Engineering,Institute of Applied Chemistry,Huaqiao University,Xiamen 361021,Fujian,China);Research progress of antibacterial activity of chitosan and its derivatives[J];化工进展;2011-01
3 YANG Jian, YANG Li-fang,YANG Xiu-ling,ZUO Jian,WANG Shao-wei,XU Jian,YI Ding-hua. Department of Cardiovascular surgery,Xijing Hospital,Fourth Military Medical University,Xi'an 710032,China;Use of chitosan dressings in patients with congenital heart disease underwent interventional therapy[J];中国心血管杂志;2010-06
4 ZHOU Wen-wu,GU Hai-zheng High Vocational School,China Pharmaceutical University,Nanjing 211198,China;Application of chitosan micro/nano particles in targeted drug delivery system[J];药物评价研究;2010-04
5 YING Yue-qing,WANG Hong-lei (Beijing Products Quality Supervision and Inspection Institute,Beijing 100026,China);EXPERIMENTAL OBSERVATION ON ANTIBACTERIAL ACTIVITY OF NON WOVEN FABRICS MADE FROM CHITOSAN[J];中国消毒学杂志;2010-04
6 Adam Low, Melanie Love, Robert Walt, Katherine Kane, Jason Goh, Department of Gastroenterology, Queen Elizabeth Hospital, University Hospital Birmingham NHS Foundation Trust, Edgbaston, Birmingham, B15 6HT, United KingdomBertus Eksteen, Department of Liver Medicine, Queen Elizabeth Hospital, University Hospital Birmingham NHS Foundation Trust, Edgbaston, Birmingham, B15 6HT, United Kingdom;Understanding of chemoprophylaxis and concordance in inflammatory bowel disease[J];World Journal of Gastroenterology;2010-05
7 YIN Gang1, HOU Chunlin1, LIU Wanshun2, HAN Baoqin2, WEI Changzheng1, LIU Shuangli1, GUO Xingfeng1, YU Bing3.1Department of Orthopaedics, Changzheng Hospital of the Second Military Medical University, Shanghai, 200003, P.R.China;2Biotemed Biological Material Co.Ltd of Qingdao;3Department of Cell Biology of the Second Military Medical University.;EXPERIMENTAL STUDY ON HEMOSTASIS OF A NEW CHITOSAN HEMOSTATIC POWDER[J];中国修复重建外科杂志;2009-11
8 QIN Rong-gui1,WU Jian-wei2*,GUO Guo2,FU Ping2 (1.Pharmacological College,Guiyang Medical University,Guiyang,Guizhou 550004,China;2 Basic Medical College,Guiyang Medical University,Guiyang,Guizhou 550004,China);Experimental Study on the Acute Toxicity of Flyblow Chitosan in Mice[J];时珍国医国药;2009-03
9 LI Ruo-hui,CHENG Yan-ling(Biochemical Engineering College of Beijing Union University,Beijing 100023,China);New Dosage Forms Based on Chitosan as Drug Carriers[J];北京联合大学学报(自然科学版);2008-03
10 HE Yang-hu1,HE Wen1,LI Yong2, HE Ping-ping2,XIAO Li-hai2,SUN An-qi2 (1.Department of Pharmacy of Renmin Hospital of Wuhan University,Hubei Wuhan 430060,China;2.College of Pharmacy,Wuhan University,Hubei Wuhan 430072,China);Study on the effect of N-trimethyl chitosan chloride on the nimesulide liposomal gel in vitro[J];中国医院药学杂志;2008-09
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