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《Chinese Medical of Factory and Mine》 2008-01
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Effect of therapy of microecosystem on helicobacter pylori infection

WEI Shu-jing,YANG Zhu-fang,ZHANG Yuan-qing,LU Xiao-lan.Department of Gastroenterology,The 521 Hospital of Ministry of Weapon Industry,Xi'an 710065,China  
Objective To observe the curative effect of lactobacillus complex capsules on helicobacter pylori(Hp).Methods The observed 59 cases who suffered from stomach ulcer and infected with H.pylori were divided into two groups(control group and treatment group).The treatment group(22 cases) was served with omeprazole for one week,lactobacillus complex capsules plus ulcerlmin for four weeks.The control group(37 cases) was served with omeprazole,amoxicillin and clarithromycin for one week,ulcerlmin for four weeks.When four weeks after the course of treatment,14C-Urea Breath Test and gastroscope were re-examined,and the ulcer healing rate,Hp eradication rate and the degree of inflammatory cell infiltration in gastric mucosa before and after treatment were observed.Results In the treatment group and control group,the stomach ulcer healing rates were 86.36% and 91.88% and the Hp eradication rates were 72.73% and 81.08%,respectively.Compared with the control group,the healing rates and the eradication rates in the treatment group had no significant difference(P0.05).The degree of inflammatory cell infiltration in mucosa was better improved after treatment in the two groups(P0.05).Conclusions The effect of lactobacillus complex capsules on controlling Hp infection is similar to that of antibiotics.
【CateGory Index】: R573.1
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