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《Chinese Journal of Comparative Medicine》 2008-04
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Effects of Pentobarbital Sodium, Chloraldurat and Ethylcarbamate on Hematology in Female SD Rats

KANG Ai-jun~1, ZHANG Kuo~1, TIAN Feng~1, LIU Hong-yan~2, ZHENG Zhen-hui~1 (1. Department of Laboratory Animal Sciences, Peking University Health Center, Beijing 10083, China;2. Institute for Biochemical Drug Control, Beijing 100035)  
Objective To investigate the effects of pentobarbital sodium,chloraldurat and ethylcarbamate on hematology in female SD rats. Method Female SD rats were anesthetized by intraperitoneal injection of pentobarbital sodium,chloraldurat and ethylcarbamate, respectively. Blood biochemical parameters and blood cytological indexes were determined with blood taken from retro-orbital plexus at 20 minutes after drug injection. Results Some blood biochemical parameters and blood cytological indexes of anesthetized rats showed significant difference compared with that in normal rats. Conclusion Anaesthesia do affect some of hematological values in female rats, therefore, scientific researcheres should choose appropriate anaesthetics to avoid un-wanted effects.
【CateGory Index】: R-331
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【Co-citations】
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