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《China Journal of Orthopaedics and Traumatology》 2007-01
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Core decompression combined with implantation of self-multipotent stem cell and decalcified bone matrix for treatment of early femoral head necrosis

ZHANG Jian-hua,LI Ju,TONG Pei-jian,JI Wei-feng.Department of Orthopaedics and Traumatology,the Hospilal of Zhejiang Province of TCM,Hangzhou 310006,Zhejiang,China  
Objective: To study therapeutic results of core decompression combined with implantation of self-multipotent stem cell and decalcified bone matrix(DBM) for early femoral head necrosis.Methods: Among 80 patients with early femoral head necrosis(96 hips),43 patients were male and 37 patients were female,age ranging from 21 to 62 years(average of(38.4 years).)Unilateral head necrosis occurred in 64 hips and bilateral head necrosis occurred in 16 hips.The average medical history was 1.4 years ranging from 8 months to 3 years.According to standard of ARCO staging,62 hips were stage Ⅰ and(34 hips) were stage Ⅱ.All the patients were treated with core decompression combined with implantation of self-multipotent stem cell and DBM.Clinical effect was analyzed according to clinical symptoms,the score of hip joint function,the films of(X-ray) and CT before and after operation.Results: Fifty-two patients(61 hips)were followed up more than 2 years.Forty-six hips obtained excellent results,10 hips got relief of clinical symptom,5 hips had no improvement,the rate of excellent and good was 91.8%(56/61).The averagely Harris score increased from preoperative 49.1±7.5 to postoperative 75.2±5.9((P0.01).)Conclusion: Core decompression combined with implantation of!self-multipotent stem cell and DBM is an(effective) method for early femoral head necrosis.
【CateGory Index】: R687.3
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