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《Chinese Journal of Public Health》 2009-12
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Protecive effects of Pu-erh tea on nonalcoholic fatty liver in rats

HOU Yan,XIAO Rong,XU Kun-long,et al.College of Longren Pu-erh Tea,Yunnan Agricultural University(Kunming 650201,China)  
Objective To evaluate protective effects of Pu-erh teas on high-fat diets induced nonalcoholic fatty liver in SD rats.Methods Eighty SD rats were divided into groups of normal control,model of high-fat diet,Pu-erh raw tea or Pu-erh mature tea treated groups(0.5,1.5,and 3.0 g/kg·bw,repectively).All rats were sacrificed after 30 days' test feeding.Biochemical parameters including superoxide dismutase(SOD),glutathion peroxidase(GSH-PX),malondialdehyde(MAD) and total cholesterol(TC) in blood serum were determined,and pathological changes of the liver were observed.Results With different dose of Pu-erh tea,hepatic steatosis were improved in dose-response and dose-dependent manner.The activity of SOD,GSH-PX in blood increased significantly,and the level of MDA and TC decreased significantly(P0.5).Conclusion Pu-erh tea could suppress oxidative stress-lipid peroxidation in liver cells,and improve the pathological damages of liver effectively.The fatty liver was improved by reducing the lipid deposition and oxidative damage,which may be the mechanism of the effects of Pu-erh tea.
【Fund】: 国家科技支撑计划课题(2007BAD58B04);; 农业部现代农业产业技术体系建设专项资金资助项目
【CateGory Index】: R575.5
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