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《CHINESE JOURNAL OF HYPERTENSION》 1997-02
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Plasma Nitric Oxide and Endothelin in Patients with Essential Hypertension

Hu Chunsong 1, Luo Wei 1, Zhang Runxiang 2, Su Hai 1, Long Yidao 1 (1.Department of Cardiology, 2.Research Laboratory,The Second Affiliated Hospital of Jiangxi Medical College,Nanchang)  
Aim To survey the changes of plasma nitric oxide (NO) and endothelin (ET) in hypertension.\ Methods\ Sixty hypertensive patients,average age 54 5 years,male 31 cases and female 29 cases,were examined the plasma nitrite by colorimeteric method and the plasma endothelin by RIA method.\ Results\ The nitrite level was reduced and the ET was increased markdly in hypertensive patients, the change was correlated to the severity of disease.\ However,there seems no significant difference between the different duration of hypertension .\ Conclusion\ The unbalancy of the two factors released by the vascular endothelial cell may be the important causes of the hypertension.
【CateGory Index】: R544.1
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