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《Chinese Journal of Respiratory and Critical Care Medicine》 2010-04
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Application of Modified EcoScreen Condenser in Ventilated Patients for Collecting Exhaled Breath Condensate

ZHANG Wen-bin,CHEN Jian-rong,CAI Ying-yun.Department of Emergency Medicine,Second Affiliated Hospital of Nantong University.Nantong,Jiangsu,226001,China  
Objective To investigate the feasibility of collecting exhaled breath condensate (EBC) from artificially ventilated patients with modified EcoScreen condenser.Methods ①In vitro test with lung simulator:the modified EcoScreen condenser was connected to lung simulator and mechanically ventilated for 60 min through three different types of connected tube as follows:dry ventilator pipe disconnected to humidifier,connected to the unheated humidifier,and connected to heated humidifier.Meanwhile,the changes of the peak pressure of inspiration (PI) and tidal volume (VT) were observed.The volume of condensate was measured at last.②In vivo test from artificially ventilated patients:10 patients were artificially ventilated and their EBCs were collected with the modified EcoScreen condenser through dry pipe disconnected to humidifier for 20 min.The changes of PI,VT,respiratory frequency(f),heart rate(HR),mean arterial blood pressure (MAP),and blood oxygen saturation (SpO2) were observed.Results ①In vitro test with lung simulator:At the end of the ventilating through the dry pipe disconnected to humidifier for 60 min,2.2 mL condensate was collected.Neither the change of PI or VT nor the obstruction of the collecting tube by iced condensate were observed.The ventilating through dry pipe connected to unheated humidifier had to stop at 50 min as the obstruction of the collecting tube caused by ice.5 mL condensate was collected.It was observed that VT decreased and PI increased.After ventilation through dry pipe connected to heated humidifier for 60 min,10.5 mL condensate was collected while PI slightly increased and VT decreased.②In vivo test from artificially ventilated patients:After ventilation through dry pipe disconnected to humidifier for 20 min,2 mL EBC was collected without significance changes in PI,VT,f,HR,MAP,and SpO2.Conclusions The modified EcoScreen condenser can be favourably applied to artificially ventilated patients for collecting EBC.It is recommended to perform for 20 min through the pipe disconnected to humidifier to obtain sufficient EBC without condensate dilution and airway obstruction.It is warranted more attention to the clinical and mechanical monitoring in this procedure.
【CateGory Index】: R197.39
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