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《Chinese Journal of Rehabilitation Medicine》 2009-08
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The interaction of static magnetic field and swimming exercises on articular cartilage of rats' knee osteoarthritis

SHE Haihong,Zhang Changjie The Second Xiangya Hospital of Central South University,Changsha,410011  
Objective:To observe the prevention and treatment effect of static magnetic field and swimming exercises on articular cartilage of knee osteoarthritis in SD rats. Method:Forty male healthy SD rats were randomly divided into 5 groups:control group,osteoarthritic model group,static magnetic field therapy group,swimming exercises therapy group,and combined therapy group. and the knee joints of left hind limbs were chosen to act as osteoarthritis. After treated for 4 weeks,the rats were sacrificed and the cartilages at condylus medial femur were cut off as samples. Alcian blue staining,the cartilage general changes,Mankin' s grade,immunohistochemical integral optical density (IOD) of IL -1β and phosphorylation p38MAPK in cartilage of all groups were compared. Result:There were significant differences among all groups on the degree and uniformity of alcian blue staining,the scores of general grade and Mankin's grade,and the scores of immunohistochemical IOD of IL-1β and phosphorylation p38MAPK in cartilage (P0.05). Conclusion:Static magnetic field therapy,swimming exercises therapy and combined therapy all can lessen and/or delay the lesion of osteoarthritic cartilage in different degree.
【CateGory Index】: R454;R455
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