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《Chinese Journal of Convalescent Medicine》 2007-10
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Effect of Oxymatrine in treatment of chronic hepatitis B

Jiang Mei,Yin Shusheng,Jian Qiang,et al  
Objective To observe the effect of oxymatrine in treatment of chronic hepatitis B.Methods 248 patients with chronic hepatitis B were randomized into three groups according to the levels of ALT.Each group was randomized into therapeutic group and control group. The all groups were treated with protective liver therapy. The therapeutic groups were added with oxymatrine,600mg,i.v,drip,once daily. The therapeutic course was three months. At the end of one treatment month and three treatment month,the HBsAg negative rate,HBeAg negative rate anti-HBe positive rate and HBV-DNA negative rate were examined.Results HBeAg negative rate,anti-HBe positive rate and HBV-DNA negative rate in therapeutic groups were higher than in the control groups (P0.05,P0.01). HBsAg negative rate in the therapeutic groups was higher than in the control groups,but it was not statistically significant (P0.05). Conclusion Oxymatrine has the good effect in treatment of chronic hepatitis B.
【CateGory Index】: R259
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