Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
Add to Favorite Get Latest Update

The effect of the increase in blood cell volume on microangiopathy in diabetic patients

Yan Sunjie, Zhuo Xiaofu, Pan Shizhong, et al (Department of Endocrinology, The 1st Affiliated Hospital, Fujian Medical University, Fuzhou 350005)  
Objective To investigate the cause of increased blood cell volume and its action on microangiopathy in diabetic patients.Methods Some parameters of blood cell and Na + K + ATPase and Ca 2+ ATPase activities in erythrocyte membrane were determined by automatic blood cell analyzer, modified Hanahan's, and Luthra's methods in 52 diabetic patients and 49 normal controls. Results Activities of Na + K + ATPase and Ca 2+ ATPase in erythrocyte membrane were decreased in the diabetic patients, especially those with microangiopathy. Mean corpuscular volume (MCV) and mean platelet volume (MPV) increased and mean corpuscular haemoglobin concentration (MCHC) decreased in the patients with microangiopathy. Whereas they were normal in those without microangiopathy. The changes of MCV, MPV and MCHC were related to the decrease in both ATPase activities in erythrocyte membrane.Conclusion The increase in blood cell volume relevant to the decrease in ATPase activities were probably important factors in the pathogenesis of diabetic microangiopathy.
【CateGory Index】: R587.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 10 Hits
1 Zhou Biyan.Nanning First People's Hospital(Nanning 530002);Study on the clinical meaning of platelet's parameters varication in patients with brain infarction and diabetes mellitus[J];Guangxi Medical Journal;2002-07
2 Liu Hongyan, Liang Aiping, Yang Xiaoqiu, et al. (Outpatient Service of Chinese PLA General Hospital, Beijing, 100853);Study on the Hyperglycemia and Correlative Factors in Medical Population and its Significance in Health Education[J];Heilongjiang Nursing Journal;2004-09
3 LI Jun xia,WU Hai xia (The People's Hospital of Puyan City ,Puyang 457000, China);Comparing study of nail fold microcirculation in diabetes and nondiabetes patients[J];HENAN MEDICAL RESEARCH;2000-03
4 ZENG Bin,ZHENG Hui-feng,LIN Yi-li,et al.Department of Urology,the Second People's Hospital of Shantou,Shantou 515011,Guangdong,China;Clinical Analysis of Morphological Changes in Peripheral Blood Cells of Patients with Diabetic Nephropathy[J];Chinese Journal of General Practice;2011-02
5 SHI Yushui and LIU Wei.Hubei Provincial Corps Hospital, Chinese People's Armed Police Forces ,Wuhan 430061,China;Clinical significance of measurement of mean platelet volume in type 2 diabetic patients[J];Medical Journal of the Chinese People's Armed Police Forces;2006-11
6 SUN Qing-kai,WEN Qing-hui (Dongguan People's Hospital,Dongguan 523018,China);The volume change of blood cells in diabetic nephropathy and its clinical significance[J];China Medical Herald;2007-11
7 Cheng Weili,Ding Mingmin,He Qiang,etc;Change of blood cell parameter in the aged with hypertension、coronary heart disease and diabetes[J];Chinese Journal of Convalescent Medicine;2005-03
8 SUN Lin-lin. ( Department of Stomatology , The First Affiliated Hospital of Xinxiang Medical College ,Henan 453100, China);A survey of periodontitis, dentition defect and edentulous status in aged patients with diabetes Mellitus[J];Chinese Journal of Geriatric Dentistry;2009-01
9 NIE Ying-juan,MENG Qing-yi,ZHOU Bao-lin, et al. Emergency Department,Chinese PLA General Hospital,Beijing 100853,China;Study on the form changes of peripheral blood cells and its related factors in the primary hypertension[J];Chinese Journal of Critical Care Medicine;2004-02
10 ZHANG Kai-fang, LIU Jun, LIU Tao, et al. The Department of Orthopaedics, the Second Affiliated Hospital, Medical College, Xi'an Jiaotong University, Xi'an 710004, Shaanxi, China;Changes of Femoral Head Bone Metabolism Induced by Diabetes Mellitus[J];Chinese Journal of Rehabilitation Theory and Practice;2007-12
Chinese Journal Full-text Database 1 Hits
Chinese Journal Full-text Database 10 Hits
1 JIANG Xiao-hong,CHEN Ai-wu(Department of Pediatrics,Chaohu Second People's Hospital,Anhui 238000,China);Change of platelet parameters and its clinical significance in neonates with hypoxic-ischemic[J];Journal of Bengbu Medical College;2008-01
2 CHENG Yin mei, ZHANG Shu yum, ZHU Jian zhong (Hangzhou Sanatorium of PLA, Hangzhou 310007,China);Relationship among Diabetic Complication and Apolipoprotein, Free Radicals[J];Bulletin of Science and Technology;2001-03
3 He Tieniu,et al. People's Hospital of Yixian County of Anhui Province,Yixian 254400;The Relation Between the Increase in Blood Cell Volume and Microangiopathy in Diabetic Patients[J];Qingdao Medical Journal;2001-02
4 PU Xiu-hong,GUO Xiao-qing,QIU Meng,LI Qian,AN Tao. Department of Pediatrics,the 309th Clinical Division,General Hospital of the People′ s Liberation Army,Beijing 100091,China;Change of platelet parameters and its clinical significance in neonates with cerebral damage[J];The Journal of Practical Medicine;2006-09
5 Zhao Shuhao, Liu Donghui, Xu Rong, Huang Lingning,Pan Shizhong, Yan Sunjie, Yang Liyong(Department of Endocrinology, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350005);Effects of cilostazol on platelet parameters in the microvascular complicationsof diabetic patients[J];Tianjin Pharmacy;2005-04
6 Ge HQ,Xu YY,Cai HQ Department of Endocrinology, Second Hospital, Jilin University, Changchun 130041, Jilin Province, China;Intervention of 890 nm infrared laser intravascular irradiation in the concentrations of serum nitric oxide and oxygen free radicals in patients with diabetic polyneuropathy[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2007-05
7 DONG Xiao-wei,FANG Xin-min,LU Xiao-hong (Dept.of Laboratory,Ningxia Autonomous Region Hosp.,Yinchuan 750021);Study on the Relation Between Microvessel Lesion and 4 Indexes of Platelet in Diabetic Patients[J];JOURNAL OF NINGXIA MEDICAL COLLEGE;2000-04
8 Li Weimin; Bao Cuiyu; Yu Xiqiu et al (Department of Medical, Xianning Medical college, Xianning 437100);The Change in Hemorheology of Parameter About Diabetic Microvascular Patients[J];JOURNAL OF XIANNING MEDICAL COLLEGE;1998-03
9 Yang Fengmei, Jia Ronghe, Gao Haibin, et al. Department of Pediatrics, Yang Quan First People's Hospital, Shanxi, 045000, China;CHANGES AND SIGNIFICANCE OF PLATELET PARAMETERS IN NEONATAL HYPOXIC - ISCHEMIC ENCEPHALOPATHY[J];The Journal of Neonatology;2004-01
10 Zhang Yizhuan,Shang Guilian,Liu Jianhua.Department of Ophthalmology,Wuhan Railway Central Hospital,Wuhan 430064;A clinical study of the relationships between retinal vein occlusion,and mean platelet volume and platelet count[J];CHINESE OPHTHALMIC RESEARCH;2000-03
Chinese Journal Full-text Database 10 Hits
1 Chen Xi, Xu Jianming, Hu Naizhong, et al Department of Digestive, the Affiliated Hospital of Anhui Medical University, Hefei 230022;Effects of gastric pacing on gastric myoelectrical activity and gastric emptying in patients with gastric dysmotility[J];Anhui Medical Journal;2003-05
2 NIE Song liu,XU Xian xiang,XIA Lun zhu (Hospital of Lu′an City,Anhui Lu′an 237000,China);EFFECT OF TOTAL SAPONINS OF CODONOPSIS ON BLOOD LIPID AND NITRIC OXIDE LEVEL IN EXPERIMENTAL HYPERLIPEMIA RATS[J];Journal of Anhui Traditional Chinese Medical College;2002-04
3 JIA Zhaotong, YAN Shengli, LU Xingyi Department of Endocrinology, The Affiliated Hospital of Qingdao University Medical College, Qingdao 266021; [;THE EFFECTS OF L-ARG TEST ON INSULIN AND GLUCAGON LEVELS IN PATIENTS WITH DIABETIC ANGIOPATHY[J];ACTA ACADIMAE MEDICINAE QINGDAO;2000-01
4 Hong Xingqiu, et al(Institute of Molecular Medicine, Hangzhou 310009);Experimental Study of Pinellia Tuber on Reducing Blood-Lipid[J];Journal of Zhejiang College of Tcm;1995-02
5 HOU Zhi-yang (School of Public Management Fujian Normal University,Fuzhou 35007,China);Evolution and Its Implication of Western Social Security Concept Basis[J];Journal of University of Science and Technology Beijing;2004-04
6 Zhao Dayuan,Hou Ruoying ,Zhang Longsheng  ,et al (Dept.of Physics; Health School;  Dept.of Internal Med.,The Second Clinical College);Hemorheological change of aged patients with diabetes[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;1997-02
8 LONG Qing-lin, FANG Dian-chun,SHI Hong-tao,et al.(Gastroenterology Research Center, Southwest Hospital,the Third Military Medicial Univisity, Chongqing 40038,China);Effects of interstitial cells of Cajal in stomach on diabetic gastroparesis[J];Chongqing Medical Journal;2005-08
9 XU Long 1,YU Bao-ping 2,CHEN Ling-dan2,Lü Nong-hua1,ZHU Xuan1,CHEN You-xiang11.Department of Gastroenterology,the First Affiliated Hospital of Nanchang University,Nanchang 330006,Jiangxi,China2.Department of Gastroenterology,People's Hospital of Wuhan University,Wuhan 430060,Hubei,China;Interstitial cell of cajal regulates motility of gallbladder smooth muscle in guinea pigs[J];Academic Journal of Second Military Medical University;2010-07
10 Xu Qi, Peng Yajun, Lu Jian, Xia Fenghua, Han Lirong, Shen Wei (Department of Ophthalmology, Changhai Hospital, Second Military Medical University, Shanghai,200433);Analysis of the diabetic retinopathy in type diabetes (with 304 cases of reports)[J];ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY;1999-07
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 YUAN Shi-bin1,2 CHEN Dai-wen1,2(1.Key Laboratory of Animal Disease-Resistance Nutrition,Ministry of Education,Ya'an 625014,China;2.Animal Nutrition Institute,Sichuan Agricultural University,Ya'an 625014,China);Effects of Oxidative Stress on Blood Cell Parameters of Weanling Pigs[J];Chinese Journal of Animal Nutrition;2008-06
2 CHEN Jie.Department of Endocrinology,The Second Affiliated Hospital of Shandong TCM University,Jinan 250001,China;Study on the changes of Th1/Th2 lymphocytes subgroup in patients with type 1 diabetes mellitus complicated by vascular lesion[J];Hebei Medical Journal;2010-08
3 LI Dekui,LIU Yue,ZHU Ming'an,et al.Department of Clinical Laboratory,the Affiliated Taihe Hospital of Yunyang Medical College,Shiyan 442000,China;Clinical significance of determination of the platelet,hemorheology and coagulation parameters in patients with diabetes mellitus[J];Journal of Chinese Practical Diagnosis and Therapy;2008-11
4 ;护生口腔健康知识和口腔行为的调查分析[J];China Foreign Medical Treatment;2011-06
5 LI Bo reviewing,GAO Xiu-qiu checking(Department of Oral Medicine,Second Clinical Hospital,Liaoning Medical University,Jinzhou 121004,Liaoning,China);Research on the relationship between Interleukin-18 gene and diabetes and periodontal disease[J];Journal of Medical Postgraduates;2010-03
6 CHEN Guan-fen,LUO Xiu-rong,ZHENG Hong-yu,WU Hai-ying,ZHANG Huan-bo(1)Dept.of Internal Medicine,The 2nd People's Hospital of Qujin City,Qujing Yunnan 655000;3)Dept.of Emergency,The 1st Affiliated Hospital of Kunming Medical College,Kunming Yunnan 650032;3)Kunming Shifa Hospital,Kunming Yunnan 650032,China);A Clinical Investigation of Compound Dilong Capsule in the Treatment of Type 2 Diabetics Nephropathy[J];Journal of Kunming Medical University;2011-02
7 ZHOU Bo-feng(Department of Laboratory,Jiangbin Hospital of Guangxi Zhuang Autonomous Region,Nanning 530021,China);Clinical significance of changes of platelet parameters in type 2 senile diabetics[J];Internal Medicine of China;2009-02
8 LI Jie,WANG Jun-hong.Department of Stomatology,the First Hospital of Beijing University,Beijing 100034,China;The Latest Researching Progress of the Relationship between Periodontitis and General Systemic Disease[J];Chinese General Practice;2006-14
9 She Yanzhao, Liu Chunyan (Nursing College of Tianjin Medical University, Tianjin 300070 China);Common oral complications of diabetes mellitus patients and its preventive nursing measures[J];Chinese Nursing Research;2006-11
10 GAO Jin.The Fenyang Hospital of Shanxi Province,Fenyang 032200,China;Relationship between the glycosylated hemoglobin and platelet parameter in diabetes mellitus with asymptomatic cerebral infarction[J];Journal of Practical Medical Techniques;2010-12
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved