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《Chinese Journal of Natural Medicines》 2006-03
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Chemical Constituents of Mangrove Plant Excoecaria agallocha

LI Xiang~(1,2),YAO Yan-Hua~(1),ZHENG Yi-Nan~(1),LIN Wen-Han~(2*),DENG Zhi-Wei~(3)(()~(1))School of Pharmacy,Jilin Agricultural University,Changchun 130118;(()~(2))National Research Laboratory of Natural and Biomimetic Drugs,Peking University,Beijing 100083;(()~(3))Analytical Center,Beijing Normal University,Beijing 100072,China  
AIM: To study the chemical constituents from mangrove Excoecaria agallocha.METHODS: Classic chromatography including HPLC was used for the isolation and purification of compounds,and extensive spectral analyses including various(()~2D?NMR) spectra were employed for structure elucidation.RESULT: Ten compounds have been isolated from this plant: 14-taraxeren-3-one(1),18-oleanen-3-one(2),3,28-dihydroxyl-lupeol(3),28-hydroxy-20(29)-lupen-3-one(4),18-oleanen-3-ol(5),dibutyl phthalate(6),diethylhexyl phthalate(7),stigmast-4-en-3-one(8) phaeophytin A(9),phaeophorbide A(10).CONCLUSION: Compounds 1 and 7 show weak inhibitory activity on HL-60 cell.
【Key Words】: Mangrove Excoecaria agallocha Chemical constituents
【Fund】: 国家高科技计划“863”课题(No.2002AA217081);; 国家自然科学基金(No.40176038)资助~~
【CateGory Index】: R284
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