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《China Modern Medicine》 2016-02
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Clinicopathological features and prognosis of colorectal cancer with ascites

WANG Hong-xu;ZHANG Ji-dong;LI Dong-ping;LU Yan-xing;LI Rui;Department of General Surgery,People′s Hospital of Yingde City in Guangdong Province;  
Objective To investigate the prognostic results of clinicopathological data in patients with colorectal cancer combined with ascites and analyze the prognosis. Methods The clinicopathological and follow up study data of 139 patients combined with ascites and 400 patients without ascites between October 1999 and January 2005 in our department were retrospectively analyzed and evaluated the prognosis between them by SPSS 19.0. Results Single factor analysis revealed that the prognostic of patients combined with ascites were associated with the factors,such as intestinal obstruction,pelvic metastatic nodal,peritoneal implantation,liver metastasis,viscera invasion,tumor location,radical degrees,tumor type,depth of infiltration,and histological classification(P0.01).Peritoneal implantation(OR=1.781,95%CI=1.131-2.804),pelvic metastatic nodal(OR =3.211,95% CI =1.196-8.623),liver metastasis(OR =3.127,95% CI =1.777-5.502),depth of infiltration(OR=2.789,95%CI=1.015-7.665) were of important factors in radical prostatectomy of colorectal cancer combined with ascites by binary Logistic analysis;survival analysis revealed that overall survival were different in whether colorectal cancer combined with ascites(1,3,5,10 year of survival rate respectively:80%,67%,60%,41% vs 58%,48%,38%,27%) and resection and lymphnodenectomy contribute to improve overall survival(P 0.05).Conclusion Patients with colorectal cancer combined with ascites indicate poor prognostic results.Patients with colorectal cancer combined with ascites underwent dissection and lymphnodenectomy can significantly improve the survival rates.
【CateGory Index】: R735.34
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