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《Chinese Circulation Journal》 2019-01
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Relationship Between Snoring and Hypertriglyceridemia in Middle-aged Chinese Population: A Cross-sectional Study

XIA Yanjie;ZHOU Long;LI Ying;GUO Min;LIU Huanhuan;WU Yangfeng;ZHAO Liancheng;Division of Prevention and Community Health, National Center for Cardiovascular Diseases and Fuwai Hospital,CAMS and PUMC;  
Objectives: To explore the relationship between different snoring characteristics(including snoring frequency, snoring sound intensity) and hypertriglyceridemia in middle-aged Chinese population.Methods: The data of 15 population samples from China Multicenter Collaborative Study of Cardiovascular Epidemiology(ChinaMUCA) conducted in 1998 were analyzed. Approximately 1 000 men and women aged 35 to 59 in each population were surveyed for cardiovascular risk factors, and participants' snoring habits(snoring frequency, snoring sound intensity). Multivariate logistic regression models were used to evaluating the relationship between snoring frequency, snoring sound intensity and hypertriglyceridemia.Results: A total of 14 175 participants were included in the analysis, according to the frequency of snoring, participants were divided into four groups, including never, occasionally(≤2 times/week), often(3-5 times/week), and always(6-7 times/week) snoring groups. The prevalence of hypertriglyceridemia in the above 4 groups was 21.3%, 28.4%, 35.4%, 37.1%, respectively(P for trend0.001). The prevalence of hypertriglyceridemia increased significantly in proportion with the increase of snoring sound intensity(P for trend0.001). After adjustment for potential confounding factors, the risk ofhypertriglyceridemia increased significantly in higher snoring frequency groups, and when body mass index was further adjusted in model 3, higher snoring frequency remained as an independent risk factor of hypertriglyceridemia. Comparing with never snoring group, the odds ratio and 95% confidence interval in occasionally, often, and always snorers were 1.12(1.01-1.24), 1.34(1.18-1.52), 1.32(1.14-1.53), respectively(P for trend 0.001). Moreover, snoring sound intensity also positively correlated with hypertriglyceridemia(P for trend 0.001). Conclusions: Both snoring frequency and snoring sound intensity positively correlate with the risk of hypertriglyceridemia in middle-aged Chinese population.
【Fund】: 国家“九五”科技攻关计划(96-906-02-01)
【CateGory Index】: R589.2
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