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《Chinese Journal of Animal Science》 2006-01
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Gene Expression and It's Modulation of Mammalian Preimplantation Embryo

YAO Ning,ZENG Shen-ming*(College of Animal Science and Technology,China Agricultural University,Beijing 100094,China)  
The pre-implantation period of mammalian development includes the formation of the zygote,the activation of the embryonic genome(EGA),and the beginning of cellular differentiation.During this period,the maternal control of development is succeeded by zygotic control,and the formation of a chromatin-mediated transcriptionally repressive state is beginning.For relieving this repressiveness,the embryonic genome is activated.The characterization of zygotic mRNA expression patterns during the pre-implantation period and their relationship tosuccessful development in vitro and in vivo will be essential for defining optimized culture conditions and nuclear transfer protocols.
【Fund】: 国家自然科学基金资助(30100133)
【CateGory Index】: Q954.4
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