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《Chinese Journal of Preventive Veterinary Medicine》 2006-06
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The in vitro antiviral activity of Radix Astragali and Radix Isatidis to porcine parvovirus

WANG Xue-bin WEI Zhan-yong CUI Bao-an HUI Yong-hua XU Duan-hong (Engineering College of Animal and Veterinary Science,Henan Agricultural University,Zhengzhou 450002,China)  
To study the anti-PPV(porcine Parvovirus)activity and mechanism of Radix Isatidis and Radix Astragali,Radix Isatidis and Radix Astragali were used separately and then mixed to challenge the PPV(porcine Parvovirus)cultured in PK-15 cell based on the inhibition to cytopathogenic effect(CPE).Minimal inhibitory concentration(MIC)and minimal stop concentration(MSC)had been determined directly and indirectly.The results showed that the anti-PPV cutivities of 1:1 mixture of Radix Astragadi and Radix Isatidis were significantly higher than that of Radix lsatidis,their MIC is 0.31 mg/mL, and their MSC is 0.075 mg/mL.
【Fund】: 河南省重点科技攻关(项目编号:0223033400)
【CateGory Index】: S858.28;S853.7
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