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《Chinese Journal of Preventive Veterinary Medicine》 2009-04
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Evaluation of the virulence of 6 Eimeria spp.Lanzhou strains

YAN Hong-bin,TIAN Guang-fu,JIA Wan-zhong,LIU Hong-xia,ZHANG Dong-feng,CAI Xue-peng(Key Laboratory of Veterinary Parasitology of Gansu Province/State Key Laboratory of Veterinary Etiological Biology Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou 730046,China)  
This experiment examined the virulence of 6 Eimeria spp.Lanzhou strain by infecting Jiahehuang female broilers at various dosages.Nine trial groups,including negative control group(NC) and 8 challenge infection groups(1-8) were tested.The average relative growth ratio(RGR) of 8 groups was 100 %,77.23 %,77.02 %,76.42 %,72.86 %,63.91 %,67.19 % and 42.06 %,respectively.The RGR of NC group was significantlg higher than other groups(p0.01).The RGRs of the 1st and the 2nd group were significant higher than the 5th and the 6th groups(p0.01) and the 7th group(p0.01).The feed conversion ratio(FCR) in the 7th group was significantlg higher than other groups.The OPG of the 7th group(150.11×104) was significantly higher than the 1st(3.05×104),the 2nd(2.35×104),the 3rd(32.20×104),the 4th(62.23×104) and the 5th group(60.45×104)(p0.01) after challenge.The mortality rate of 9 groups was 0,5.0 %,5.0 %,15 %,25 %,40.0 %,45.0 %,95 % and 100 %,respectively.These results indicated that the Eimeria spp.strains isolated from Lanzhou are highly virulent.Chickens infected with 6×104 oocysts suffered significant suppression in growth and 50 % mortality.The best challenge dosage was 1×104-1×105(each Eimeria spp.).
【Fund】: 863计划(2006AA10A207);; 国家科技支撑计划(2007BAD40B04);; 国家自然科学基金(30872369)
【CateGory Index】: S858.31
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