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The Study on the Risk and PAR of Cigarette Smoking to Lung Cancer

Zhou Baosen; Liu Keli; He Anguang;et al(Lung Cancer Laboratory,Cancer Institute, China Medical University, Shenyang,110001)  
ne thousand and fifty six cases of lung cancer which were identified pathologically Were dis-cussed.The sections were stained with HE,PAS-ab and Keratin. There were 1035 patients with lungcancer who had history of cigarette smoking at the same time.We collected 116 patients without malig-nant diseases by graduated sampling as their sex and age. The results showed that:The Odds Ratio(OR)values of squamous cell carcinoma,small cell carcinoma and large cell carcinoma cases withcigarette smoking were 3.30(95%CI 2.12~5.14),2.92(95%CI 1.63~5. 22)and 2.97(95%CI 1.36~6.51) respectively,All three types had dose- response relat ions with the amount and duration ofcigarette smoking,And adenocarcinoma did not relate to cigarette smoking,OR 1.34(95%CI 0. 85~2. 10).In order to estimate the effection of cigarette smoking with lung cancer in Shenyang city,popula-tion attribute risk(PAR)were calculated. PAR ofSquamous cell carcinoma,small cell carcinoma andlarge cell carcinoma are and 0.45 respectively.
【Fund】: 国家“八五”科技攻关
【CateGory Index】: R734.202
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