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《Chinese Pharmaceutical Journal》 2013-21
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Chemical Constituents of the Aerial Parts of Emilia sonchifolia(Ⅱ)

SHEN Shou-mao;ZHANG Jing;LI Guang-zhi;LIU Chun-ming;LU Hui;SI Jian-yong;Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences,Peking Union Medical College;School of Pharmary,Yancheng Teachers' University;Guangxi Huahong Pharmaceutical Co.Ltd.;  
OBJECTIVE To study the chemical constituents of the aerial parts of Emilia sonchifolia.METHODS The chemical constituents were isolated and purified by chromatographies on silica gel,MCI gel,ODS,and Sephadex LH-20 columns,as well as RP-HPLC.And their structures were identified on the basis of physicochemical properties and spectral data.RESULTS Eighteen compounds were obtained from the aerial parts of E.sonchifolia and identified as isorhamnetin-3-O-α-L-rhamnopyranoside(1),afzelin(2),quercetin-7-O-α-L-rhamnopyranoside(3),5,2',6'-trihydroxy-7-methoxyflavone 2'-O-β-D-glucopyranoside(4),quercetin-3-O-α-L-rhamnopyranoside(5),diosmin(6),isorhamnetin-3-O-rutinoside(7),linarin(8),vitexin(9),quercetin-7-O-β-D-glucopyranoside(10),vicenin-2(11),methyl 4-hydroxybenzeneacetate(12),3,4-dihydroxybenzeneacetic acid(13),brevifolin(14),chlorogenic acid(15),methyl chlorogenate(16),pedatisectine E(17),and uridine(18),respectively.CONCLUSION All compounds are isolated from this genus for the first time except compounds 5 and 11.
【Fund】: 国家“重大新药创制”科技专项(2011ZX09307-002-01 2012ZX09301-002-001)
【CateGory Index】: R284
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