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《Chinese Journal of Hospital Pharmacy》 2009-13
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Observation of gypenosides to the mouse respiratory inflammation and immunoenhancement effect

LIU Yu-ping,YU Miao,YIN Xiang-min (Department of Pharmacology,Heze Medical Collage,Shandong Heze 274030,China)  
OBJECTIVE To study the immunomodulating,antitussive and expectorant effect of Gypenosides.METHODSCough model was induced by citric acid in guinea pig,and phenol red expectoration test. Carbon clearance test was used. RESULTS The tests showed that Gypenosides had significant antitussive effect on guinea pig induced by citric acid. Gypenosides could increase the index of K and α in carbon clearance test,increased the weight of spleen and thymus. CONCLUSION Gypenosides had significant antitussive and expectant effect,and could greatly enhance immunological function.
【CateGory Index】: R285.5
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