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《Chinese Acupuncture & Moxibustion》 2009-04
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Observation on therapeutic effect of acupoint application on dysmenorrhea of excess syndrome and effect on prostaglandins

WANG Shu-xin~1,LU De-jian~2,LI Yan-hui~1(1.Department of Acupuncture and Moxibustion,The First Affiliated Hospital of Guangzhou University of TCM,Guangzhou 510405,China;2.Graduate Student,The First Affiliated Hospital of Guangzhou University of TCM)  
Objective To observe therapeutic effect of acupoint application on dysmenorrhea of excess syndrome and its effect on prostaglandins.Methods The patients with primary dysmenorrhea of excess syndrome were randomly divided into an application group and a medication group.The application group of 31 cases were treated with application of Chinese medicine composed of Zhinanxing(Rhizoma Arisaematis),Sanleng(Rhizoma Sparganii), Ezhu(Rhizoma Zedoariae),etc.at Zhongji(CV 3),Guanyuan(CV 4),Qihai(CV 6);and the medication group of 30 cases were treated with oral administration of Tianqi Tongjing Capsules.The scores for the pain degrees and the duration of dysmenorrhea were observed and prostaglandin F_(2α)(PGF_(2α)) and prostaglandin E_2(PGE_2) contents in peripheral blood were determined before and after treatment.Results The total effective rate of 93.5%in the application group was significantly better than 73.3%in the medication group(P0.05);after treatment,the scores of the symptoms were significantly decreased in the two groups(both P0.01),with more obvious improvement in the application group than the medication group(P0.01).The PGE_2 content was significantly increased,and the PGF_(2α) content and PGF_(2α)/PGE_2 were significantly decreased in the application group(all P0.01).Conclusion Acupoint application has a better therapeutic effect on dysmenorrhea of excess syndrome and has benign regulative action on synthesis of prostaglandins in the patients with primary dysmenorrhea.
【Fund】: 广东省中医药局科研项目:A 2007031
【CateGory Index】: R246.3
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