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《Chinese Journal of Clinical Oncology and Rehabilitation》 2016-02
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Effects of sevoflurane inhalation anesthesia on blood rheology in patients with different ages of digestive tract cancer

ZHANG Wei-qing;HAO Jian-li;Department of anesthesia,Cancer Hospital of Liaoning Province;  
Objective To explore the effects of sevoflurane inhalation anesthesia on blood rheology in patients with different ages of digestive tract cancer. Methods From March 2010 to March 2013,120 cases of digestive tract cancer received treatement in Liaoning Provincial Cancer Hospital were selected as objects,according to the difference age,they were divided into group A( age 60 yr old) and group A( age ≥ 60 yr old),each group had 60 cases. All patients were treated by radical surgery and anesthesia induction. The maintenance of anesthesia was maintained with sevoflurane,remifentanil,and ammonium bromide. The changes of blood flow and the changes of red blood cells were analyzed. Results After anesthesia,Hηb,Mηb,Lηb,ηb and ηr of T1 in patients of group A were reduced than those of T0,with significant difference( P 0. 05 for all). Hηb,Mηb,Lηb,ηb and ηr of T1 in patients of group B were reduced than those of T0,with significant difference( P 0. 05 for all). Hηb of group B was reduced remarkably than that in group A,with significant difference( P 0. 05). Erythrocyte aggregation index( EAI) at T1 in two groups were reduced than that at T0,with significant difference( P 0. 05 for all). Erythrocyte deformation index( EDI) at T1 in group B was decreased than that at T0,with significant difference( P 0. 05),but EDI at T1 in group A was not remarkably changed,without significant difference( P 0. 05). Erythrocyte rigidity index( ERI) at T1 in group B was decreased than that at T0,with significant difference( P 0. 05). Conclusion Sevoflurane inhalation anesthesia can significantly reduce the blood rheology,reduce the blood viscosity,reduce the possibility of thrombosis,improve the safety of operation of patients with digestive tract tumor.
【CateGory Index】: R614;R735
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【Citations】
Chinese Journal Full-text Database 4 Hits
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【Co-citations】
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1 Somchai Amornyotin;Department of Anesthesiology and Siriraj Gastrointestinal Endoscopy Center,Faculty of Medicine Siriraj Hospital,Mahidol University;;Sedation-related complications in gastrointestinal endoscopy[J];World Journal of Gastrointestinal Endoscopy;2013-11
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4 WANG Hui-de1,ZHONG Qing1,YANG Yi-lin2,YANG Yu2,LV Lan2,TANG Xian-ling3△(1.Department of Anesthesiology,Jianyang People′s Hospital,Jianyang,Sichuan 641400,China;2.Department of Anesthesiology,Mianyang Central Hospital,Mianyang,Sichuan 621000,China;3.Affiliated Hospital,Luzhou Medical College,Luzhou,Sichuan 646000,China);Clinical relationship between hemodynamic and hemorheologic changes during propofol intravenous anesthesia in elderly patients with colorectal cancer[J];检验医学与临床;2011-18
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【Secondary Citations】
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1 YAN Hong-jiang,WANG Ren-ben Department of Radiation Oncology,Shandong Tumor Hospital,Jinan 250117,P.R.China;Progress in research of preoperative radiotherapy for rectal cancer[J];中华肿瘤防治杂志;2010-12
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