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《Chinese Journal of Clinical Oncology and Rehabilitation》 2019-05
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Insulin pump in patients with malignant tumors complicated with diabetes on chemotherapy for blood glucose control

LI Yi-jia;WANG Xiao-xue;WANG Ye-ju;LIU Hong-li;WANG Yi-meng;WEI Zhi;YANG Kai;Department of Endocrine,Central Hospital of Hanzhong;  
Objective To investigate the clinical significance of using insulin pump to control blood glucose in patients with malignant tumors complicated with diabetes during chemotherapy. Methods From March 2017 to October 2018,68 patients with malignant tumors complicated with diabetes on chemotherapy were selected and divided into an observation group and a control group according to the method of blood glucose control. Both groups received treatment for blood glucose control under the original chemotherapy regimens. The observation group received continuous subcutaneous injection of insulin aspart using insulin pump and the control group received NovoRapid or Novolin N. By detecting fasting blood glucose,2-h postprandial blood glucose,glycosylated hemoglobin levels,time to reach the target blood glucose,dosage of insulin and incidence of hypoglycemia before and after treatment,curative efficacy was evaluate in the two groups of patients. Results The levels of fasting blood glucose,2-h postprandial blood glucose and glycosylated hemoglobin were significantly lower in the observation group than in the control group(P 0. 05).The time to reach the target blood glucose the dosage of,and the incidence of hypoglycemia were lower in the observation group than in the control group(all P 0. 05). Conclusion Insulin pump in the treatment of blood glucose has good efficacy with low incidence of hypoglycemia and high safety in patients with malignant tumors complicated with diabetes,which is worthy of clinical promotion.
【CateGory Index】: R587.1;R730.53
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