Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Clinical Oncology》 2006-08
Add to Favorite Get Latest Update

Empirical Studies on Quercetin for Inhibition of Proliferation ofhuman Uterine Cervix Cancer HeLa cells

Zhang Jie Lü Cai Zhang Ping-an et al Department of Urology, People's Hospital of Wuhan University, Wuhan  
Objective: To investigate inhibition of quercetin (Que) on cell proliferation of the human uterine cervix cancer HeLa cells. Methods: Colorimetric MTT-assay was used to measure the Inhibition ratio of Que on human HeLa cells. The proliferation cycle of HeLa cells was determined using flow cytometry. Results: Que 10-160umol/L inhibited the proliferation of HeLa cells with different ratios and showed the time- and dose-dependent relationships. The augment of G1 ratio in the proliferation cycle of Hela cells presents a dose-dependent manner. Conclusion: Que can inhibit the proliferation of Hela cells and might induce the apoptosis by restrained cell cycle at G1.
【Fund】: 湖北省计生委基金项目资助(编号:301140238)
【CateGory Index】: R737.33
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 7 Hits
1 WU Xiaofen HONG Chengjiao GUO Wenxiu PAN Yanling ZHANG Baoguo(School of Radiation Medicine and Public Health,Medical College of Soochow University,Jiangsu Provincial key Laboratory of Radiation Medicine and Protection,Suzhou 215123,China);Effect of Quercetin on radio-sensitivity of HeLa cells[J];Journal of Radiation Research and Radiation Processing;2011-02
2 HUANG Jing,ZHANG Wei,LI Fumin,LI DanDept.of Gynecology and Obstetrics,Renmin Hospital of Wuhan University,Wuhan 430060,China;Effect of Quercetin on the Expression of Nm23 Gene in HeLa cells[J];Medical Journal of Wuhan University;2009-05
3 LI Run-qing1,SHAN Bao-en21.Center of Clinical Laboratory,Affiliated Beijing Youan Hospital of Capital Medical University,Beijing 100069,P.R.China2.Research Center,Affiliated Fourth Hospital of Hebei Medical University,Shijiazhuang 050011,P.R.China;Correlation between anti-tumor activity of quercetin and the inhibitive effect on Wnt/β-catenin signaling pathway[J];Chinese Journal of Cancer Prevention and Treatment;2008-21
4 Zhang Yonggang,Zhang Jie,Fan Hong,et al.Department of Laboratory Medicine,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,China;Effect of Quercetin on the expression and growth of Bcl-2 in lung adenocarcinoma cancer cell line A549.[J];Sichuan Medical Journal;2007-10
5 Wang Haiyan Wang Gaofagn Lin Gan Yu HaizhongDepartment of Chemistry and Biologic Science,Xiangfan College(Xiangfan Hubei 441053,China);Effect of Chinese Herbal Medicine on the Cell Cycle of Hela Cells[J];Journal of Sichuan of Traditional Chinese Medicine;2007-08
6 WANG Chong1,2,TAN Sai-nan2,3,LU Cai-ling2,YAO Nan1,2,MA Xu2(1Graduate School of Peking Union Medical College,Beijing 100730,China;2Dept of Genetics,National Research Institute for Family Planning;3Family Planning Institute of Hunan Province);The research of quercetin on tumor suppression of conlon cancer[J];Journal of Shanxi Medical University;2009-06
7 Yin LP LI G Fang G;Progress on the Experiment Study of Mechanism of Action of TCM Bioactive Component Induced HeLa Cell Apoptosis[J];Chinese Medicine Modern Distance Education of China;2008-11
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LI Hong-hui, LIU Xiu-fang,YANG Hui-fang(Department of Environmental Health, Ningxia Medical College,Yinchuan 750004,China);Effects of Lycium Barvarum Polysaccharides on Reproductive System in Rats with Chronic Psychologic Stress[J];Carcinogenesis,Teratogenesis & Mutagenesis;2008-03
2 ZHANG Ni-Na1, BU Ping2, ZHU Hai-Hang1, SHEN Wei-Gan2 1. Department of Gastroenterology, Subei People's Hospital, Yangzhou, Jiangsu, 225001, P. R. China 2. Institute of Integrative Traditional Chinese and Western Medicine, Medical College, Yangzhou University, Yangzhou, Jiangsu, 225001, P. R. China;Inhibitory Effects of Scutellaria barbatae D. Don on Tumor Angiogenesis and Its Mechanism[J];Chinese Journal of Cancer;2005-12
3 FENG Qing jie 1,DU Bai shan 2, SHU Chang △,LI Gang # ,SUN Li qun * (1. Department of Otorhinolaryngology and Head Neck Surgery,Second Hospital,Jilin University, Changchun 130041,China;2. Department of Anesthesiology, Second Hospital, Jilin University,Changchun 130041,China);Study on mechanism of Hep-2 cell apoptosis induced by high temperature and its effect on cell cycle progress[J];Journal of Jilin University of (Medicine Edition);2004-01
4 JIANG Wen hua, CHEN Dong , DONG Zhi yong, MENG Xiao ting (Department of Histology and Embryology,School of Basic Medical Sciences,Jilin University, Changchun 130021, China);Effect of LaCl_3 on growth of CBRH-7919 cells[J];Journal of Jilin University of (Medicine Edition);2004-03
5 ZHOU Li-xiang,LUO Yi-nan~,FU Shuang-lin,GE Peng-fei,ZHUANG Han-ting(Department of Neurosurgery,First Hospital,Jilin University,Changchun 130021,China);Effect of quercetin on proliferation of rat glioma C6 cells[J];Journal of Jilin University(Medicine Edition);2006-02
6 LI Jian~1,LI Feng~1,PANG Ai-zhi~(1*),FENG Xiu-yan~2(1.Department of Obstetrics and Gynecology,Second Hospital,Jilin University,Changchun 130041,China;2.Department of Obstetrics and Gynecology,Central Hospital of Songyuan City of Jilin Province,Sonyuan 138001,Chima);Effects of curcuma on different phases of Hela cell cycle[J];Journal of Jilin University(Medicine Edition);2006-04
7 YU Rong~1 LIU Qingling~1 ZHAO Dongmei~21 Yantai Yuhuangding Hospital,Laishan Branch,Yantai 264003;2 Binzhou Medical College;Cylostatic of action elemene on human cervix cancer Hela cells[J];Journal of Binzhou Medical College;2006-02
8 Xia Weimu, Chen Qi, Zhang Limin, Chen Shiming (Division of Radiation Medicine, Faculty of Naval Medicine, Second Military Medical University, Shanghai, 200433);Experimental study on the scavenging of active oxygen species by flavonoids[J];ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY;1997-04
9 LIANG Ke ming, XIE Yan hua, SHI Mei, WANG Si wang, WANG Xiao juan (Radiotherapy Center, Xijing Hospital, Fourth Military Medical University, Xi'an 710033, China);Inhibitory effect of Ardipusillide on human cervical carcinoma cells[J];Acta Academiae Medicine Militaris Tertiae;2002-06
10 HUANG Zeliang,ZHOU Xi,CHEN Zhongdong,et al. (The Second People′s Hospital of Huaihua,Huaihua 418400,China);Apoptosis and activity change of telomerase induced by paclitaxel in cervical cancer HeLa cells[J];Chinese Journal of Clinical Obstetric and Gynecology;2005-03
【Secondary References】
Chinese Journal Full-text Database 9 Hits
1 HE Guo-yang1,LI Wei2,JIAO Hong-li3,et al.(1.Department of Pathology;2.Central Laboratory of the Second Affiliated Hospital;3.Department of Histology and Embryology,Xinxiang Medical Universerty,Henan 453003,China);Reversal effects of ginsenoside Rg1 on apoptosis of human umbilical vein endothelial cells induced by AngⅡ[J];Chongqing Medicine;2010-19
2 CHEN Xiao-yin,WANG Zong-hua,ZHANG Fei-fei,LI Yan-hui,XIA Yan-zhi(Laboratory of Fiber Materials and Modern Textile,the Growing Base for State Key Laboratory,Qingdao University,Qingdao 266071,China);Electrochemical Study for the Quercetin at Poly(p-Aminobenzene Sulfonic Acid) Modified Electrode[J];Journal of Qingdao University(Engineering & Technology Edition);2010-01
3 TANG Lei,YANG Yang,YIN Jiang-xia,ZHAO Chang-lin Department of Oncology,Xinhua Hospital Affiliated to Dalian University,Dalian 116021,P.R.China;Correlation between Survivin,β-catenin and recurrence,metastasis of rectal cancer[J];Chinese Journal of Cancer Prevention and Treatment;2010-11
4 YANG Chao-hua,LI Guo-ping,YOU Chao,et al.Department of Neurosurgery,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,China;Effect of phenylacetate on the expression of Bcl-2,Bax and Caspase-3 in rat C6 glioma cells[J];Sichuan Medical Journal;2008-08
5 WANG Bin,YU Zhen-hai Department of General Surgery,Affiliated Qianfoshan Hospital,Shandong University,Jinan 250014,P.R.China;Research status of CDH17,a new member of cadherin superfamily,and gastric cancer[J];Chinese Journal of Cancer Prevention and Treatment;2011-12
6 A-Cheng Zhou,the First Clinical College of Nanjing University of Traditional Chinese Medicine,Nanjing 210046,Jiangsu Province,China Hei-Ying Jin,National Medical Center for Colorectal Care,the Third Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing 210001,Jiangsu Province,China Chun-Xia Zhang,Shui-Ming Wang,Graduate School,Nanjing University of Traditional Chinese Medicine,Nanjing 210001,Jiangsu Province,China;Advances in understanding preventive and therapeutic effects of quercetin against colon cancer and mechanisms involved[J];World Chinese Journal of Digestology;2011-09
7 CHEN Jing-lin,LIU Jian-jun.(Department of Urology,Affiliated Hospital of Guangdong Medical College,Zhanjiang 524023,China);Research Progress on Quercetin-induced Tumor Cell Apoptosis[J];Medical Recapitulate;2010-01
8 YIN Wen-xuan1,WANG Xing-yong1,WANG Jian-huai1,ZHUANG Hong2,SUN Kang1,LI Li1 (1.School of Chemical Engineering and Technology,China University of Mining & Technology,Xuzhou,Jiangsu 221008,China;2.School of Chemistry and Biological Engineering,Suzhou University of Science and Technology,Suzhou,Jiangsu 215009,China);FTIR Study of Rutin,Quercetin and Their Metal Complexes[J];Journal of China University of Mining & Technology;2009-06
9 GU Sheng-jiu,YANG Na,ZHU Kai-mei(College of Pharmacy,Guilin Medical College,Guilin 541004,China);Effect of Quercetin on Growth and Apoptosis of Human Nasopharyngeal Carcinoma CNE2 Cells[J];Chinese Journal of Experimental Traditional Medical Formulae;2011-13
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved