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《Chinese Journal of Osteoporosis》 2015-02
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The clinical progress in the treatment of postmenopausal osteoporosis using traditional Chinese medicine

WU Haiyang;SUO Huan;WANG Ping;Tianjin University of TCM;The First Teaching Hospital of Tianjin University of TCM;  
Postmenopausal osteoporosis is a common and popular disease in postmenopausal women.Its basic pathogenesis is metabolic imbalance of bone formation and bone absorption caused by a decline of ovarian function and a drop in estrogen level.The characteristics of the disease are bone mass loss of the whole body,the breakdown of bone micro structure,bone pain,and the increase of fracture risk.A great quantity of research indicates that traditional Chinese medicine treatment for postmenopausal osteoporosis can improve the bone mineral density of postmenopausal women and reduce the symptom of bone pain.It has distinct advantage.Currently,the research in postmenopausal osteoporosis mainly includes the experimental research of single Chinese herb and the clinical research of Chinese compound formula.This paper summarizes recent experiment development of three commonly used Chinese herbs from bone measurement index,the change of cytokines,and gene level aspects according to the pathogenesis and medication frequency of postmenopausal osteoporosis.In Chinese compound use aspects,it is believed that kidney deficiency is the main pathogenesis of postmenopausal osteoporosis.Liver and spleen deficiency and blood stigma are also involved.The paper elucidates the application of kidney-nourishing therapy in postmenopausal osteoporosis,and explores the possible future research direction for postmenopausal osteoporosis therapy.
【CateGory Index】: R259
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