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《Chinese Journal of Osteoporosis》 2017-07
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Relationship between osteoporosis and carotid atherosclerosis in the elderly

ZHANG Xiaoyan;ZHANG Nannan;General Hospital of Daqing Oil Field;  
Objective To study the relationship between osteoporosis and carotid atherosclerosis in elderly patients.Methods A total of 236 over 60-year-old people were rand omly selected as the research subjects.Bone mineral density(BMD) of the lumbar spine(L_(1-4)),femoral neck,Word's triangle,and greater trochanter was detected using dual energy X-ray absorptiometry.High resolution color Doppler ultrasound was used to detect the carotid artery medial thickness(IMT) and plaque.The basic data were also collected,including age,height,body weight,serum calcium,blood lipids,and other biochemicalresult.The subjects were divided into osteoporosis group,non-osteoporosis group,and carotid plaque and carotid artery plaque group.Results In osteoporosis group(114 cases),there were 94 cases with intimal thickening(82.46%),and 73 cases with atherosclerotic plaque(64.04%).Compared with non-osteoporosis group(122 cases),the incidence of arterial intima-media thickening(IMT≥0.9mm) and atherosclerotic plaque increased significantly in osteoporosis group(P0.05).There was a positive correlation between IMT thickening and plaque formation.IMT,age,and BMI were significantly correlated with the occurrence of osteoporosis(P0.05).The incidence of carotid atherosclerosis in women with osteoporosis was significantly higher than that in men with osteoporosis,and the difference between the two groups was statistically significant(P0.05).Conclusion There is a close relationship between osteoporosis and atherosclerosis in the elderly.Atherosclerosis is more likely to occur in patients with osteoporosis than in non-osteoporosis.The prevalence of carotid atherosclerosis in women with osteoporosis is significantly higher than that in men.
【CateGory Index】: R543.4;R580
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