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《China Journal of Chinese Materia Medica》 2006-21
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Study on chemical constituents of bark of Paeonia suffruticosa

HU Hong-yu,YANG Yu,YU Neng-jiang,ZHAO Yi-min(Institute of Pharmacology and Toxicology,Academy of Military Medical Science,Beijing 100850,China)  
Objective: To study the chemical constituents of the bark of Paeonia suffruticosa.Method: The 95% ethanol extract was re-extracted with EtOAc,and then separated and purified by column chromatography using silica gel,Sephadex LH-20 and RP-18 as packing materials.The structures were identified on the basis of spectral analysis and physico-chemical characters.Result: Six compounds were isolated and identified as(+)-catechin(1),() paeonidanin(2),() paeoniflorigenone(3),() 2,5-dihydroxy-4-methoxyacetophenone(4),() paeonol(5),() gallic acid(6).Conclusion: The compound 1 was isolsted from the genus Paeonia for the first time. The compounds 2,3 were isolated from this plant for the first time.
【Key Words】： Paeonia suffruticosa chemical constituent
【CateGory Index】： R284.1
【DOI】： CNKI:SUN:ZGZY.0.2006-21-012
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