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《China Journal of Chinese Materia Medica》 2009-14
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Steroids from Monascus purpureus metabolite

SHANG Xiaoya,WANG Ruolan,YIN Suqin,LI Jinjie,JIN Zonglian(Beijing Key Laboratory of Bioactive Substances and Functional Foods,Beijing Union University,Beijing 100083,China)  
Objective: To study the chemical constituents of Monascus purpureus metabolite.Method: The compounds were isolated by column chromatography methods,and their structures were determined by spectroscopic methods.Result: Eight compounds were isolated from the petroleum ether fraction of ethanolic extract and elucidated as stigmast-4-en-3-one(1),3-oxo-24-methylenecycloarane(2),stigmasterol(3),7β-hydroxystigmasterol(4),3β-hydroxystigmast-5-en-7-one(5),3β-hydroxystigmast-5,22-dien-7-one(6),5α,8α-epidioxyergosta-6,22-dien-3β-ol(7),sitosterol(8).Conclusion: All of the compounds were isolated from this genu for the first time except compound 3 and 7.
【Fund】: 北京市教委面上项目(KM200811417009);; 北京市优秀人才培养项目(20061D0501600234);; 北京联合大学生物活性物质与功能食品北京市重点实验室项目(LD-KZ-0605)
【CateGory Index】: R284.1
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