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《China Journal of Chinese Materia Medica》 2010-23
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Chemical constituents from roots of Pueraria lobata

LI Guohui,ZHANG Qingwen,WANG Yitao(Institute of Chinese Medical Sciences,University of Macau,Macao SAR,China)  
Objective: To study the chemical constituents in the roots of Pueraria lobata.Method: Various chromatographic methods were employed to separate of chemical constituents and the spectroscopic methods were used to elucidate the structure.Result: Twenty-two compounds were isolated and characterized as β-sitosterol palmitate(1),β-sitosterol(2),lupeol(3),lupeone(4),puerarol(5),diisobutyl phthalate(6),bis(2-ethylhexyl) phthalate(7),sophoracoumestan A(8),coumestrol(9),allantion(10),dadzein(11),formononetin(12),3′-methoxy daidzein(13),ononin(14),3′-hydroxy dadzein(15),genistin(16),dadzin(17),8-methoxy ononin(18),sissotorin(19),(-)-puerol B 2-O-glucopyranoside(20),(6S,9R)-roseoside(21) and sucrose(22),respectively.Conclusion: Compounds 1,5-8,15,18,21 and 22 were isolated from P.lobata for the first time,and componds 1,5-7,15,18,21 and 22 were isolated from the genus Pueraria for the first time.
【Fund】: 澳门科学技术发展基金(013/2008/A1);; 澳门大学研究基金(UL016/09-Y2/CMS/WYT01/ICMS)
【CateGory Index】: R284
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