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《China Journal of Chinese Materia Medica》 2012-13
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Chemical constituents contained in Macropanax rosthornii

LUO Yongming,LIU Hua,YIN Xiaoying,YE Xide,KANG Lijie(Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China)  
Objective: To study active constituents of Macropanax rosthornii in treating rheumatoid arthritis.Method: Silica gel column chromatography,preparative HPLC and modern spectrum techniques were applied for a systematic study on chemical constituents contained in M.rosthornii.Result: Twelve compounds were separated from M.rosthornii and identified as serratagenic acid(1),serjanic acid(2),betulinic acid(3),6β-hydroxy-3-oxo-olean-12-en-28-oic acid(4),3-O-α-L-arabinopyranosyl serratagenic acid(5),3-O-α-L-arabinopyranosyl serratagenic acid-29-methyl ester(6),3-O-α-L-arabinopyranosyl serratagenic acid-28-O-β-D-glucopyranosyl ester(7),scopoletin(8),β-sitosterol(9),daucosterol(10),3,4-dihydroxybenzoic acid(11),and stearic acid(12).Conclusion: Above compounds are separated from M.rosthornii for the first time.
【Fund】: 江西省自然科学基金项目(2008GQY0004)
【CateGory Index】: R284
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