Advance in studies on anti-tumor mechanism of matrine
GUO Lin-feng;TONG Shan-shan;YU Jiang-nan;XU Xi-ming;School of Pharmacy,Jiangsu University;
Matrine is one of the main active components extracted from Sophora flavescens,S. subprostrata and S. alopecuroides. In recent years,its anti-tumor activity has attracted wide attention. According to studies,matrine shows the anti-tumor effect through multiple channels such as inducing apoptosis and autophagy of cancer cells,arresting cell cycle,inhibiting tumor cell migration,angiogenesis and NF-κB,as well as the synergistic effect with chemotherapeutics. Along with the further studies on matrine's anti-tumor mechanism,it has a broad prospect for development and application in tumor clinical treatment.
【CateGory Index】： R285.5