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《China Journal of Chinese Materia Medica》 2015-12
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Relationship between efficacy exertion of diuretic traditional Chinese medicines and aquaporin

WANG Peng-cheng;ZHAO Shan;WANG Qiu-hong;KUANG Hai-xue;Key Laboratory of Chinese Materia Medica under Ministry of Education,Heilongjiang University of Chinese Medicine;  
In recent years,the discovery and studies on aquaporin have made us have a more in-depth understanding about the physiological and pathological processes of water metabolism. Over years,however,there has been no quantitative study on the target sites of diuretic traditional Chinese medicines at the molecular level. In that case,aquaporin was found to been a new target molecule to explain the efficacy exertion of diuretic traditional Chinese medicines. By studying aquaporin,researchers can understand the implicit meaning of the diuretic effect of traditional Chinese medicines and conduct quantitative studies on the diuretic effect. So far,many scholars have conducted a series of studies in the traditional Chinese medicine field by using the findings on aquaporin and made certain advances. This article provides a summary about the efficacy exertion of diuretic traditional Chinese medicines through target molecule aquaporin.
【Fund】: 国家重点基础研究发展计划(973)项目(2013CB531801)
【CateGory Index】: R285
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