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《China Journal of Chinese Materia Medica》 2017-13
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Pharmacological effect and toxicology of Sophorae Tonkinensis Radix et Rhizoma

CHEN Ying;CHEN Liang-mian;TONG Yan;YOU Yun;Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences;Key Laboratory of Chinese Internal Medicine,Beijing University of Chinese Medicine;  
Sophorae Tonkinensis Radix et Rhizoma,which has been commonly used in clinic,shows activities in antitumor,antivirus,antibacteria,analgesia,anti-inflammation,anti-liver injury,anti-oxidation and immune enhancement,but can cause liver toxicity,neurotoxicity,gastrointestinal toxicity and respiratory toxicity. Its pharmacological effect and toxicity are related to extraction process,dosage and administration time. Therefore,exploration of appropriate extraction process,toxicity-effect dosage range,toxic substance basis provides guarantee for attenuation and safe clinical medication.
【Fund】: 中医药行业科研专项(201507004-2)
【CateGory Index】: R285.5
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