Studies on the Antioxidative Effect of Constituents of Herba Epimedii (ESPS)

Zeng Nan, Meng Xianli, Zhang Yi, Lai Xianrong, Zheng Jun, Cheng Longqiong and Ren Changmao (Chengdu University of TCM 610075)  

Herba Epimedii is a traditional Yang invigorating Chinese herb widely used in clinic. The experimental results have shown that ESPS obviously increases superoxide dismutase(SOD) activity of red cells and liver in aged mice and rats,and increases glutathione peroxidase(GSH Px) activity of red cells in aged mice.On the other hand, ESPS obviously helps to reduce the content of serum and liver lipoperoxide(LPO) in aged mice and rats, as well as the content of lipofuscin(LF) in cardiac muscle of aged mice. The results suggest that being helpful in increasing SOD and GSH Px activities and inhibiting the formation of LPO and LF, ESPS may be a good antiageing agent.

【Key Words】： Herba Epimedii superoxide dismutase(SOD) ipoperoxide(LPO) glutathione peroxidase(GSH Px) lipofuscin(LF)
【Fund】： 四川省教育委员会基金
【CateGory Index】： R285.5

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