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Primary lymphomas of bone:a clinicopathologic study of 22 cases

Yang Hua; Zhao Liansheng; Zheng Zhichao; et al( Department of Pathology,Third Teaching Hospital,Norman Bethune University of Medical Sciences,Changchun,130021)  
2 cases of primary lymphoma of bone(PLB)were reported.Multiple bone involvement in two pa-tients,singular bone in twenty patients. One caseL had regional lymph nede involvement.Radiological examination revealed 91 %had diffuse lytic lesions. HistologicaI typing was performed according to working formulation. 15 formalin fixed paraffin embedded PLB specimens were studied immunohis-tochemically by use of the avidin-biotin-peroxide complex(ABC ) method to label monoclonal antibod-ies. Results:Ten neoplasms were B-cell type, three were T-cell type, the two remaining cases did not express.The ratio of primary lymphomas in this study in extranedal lymphomas is three times that re-ported in Japan and also higher than that reported in north America in recent years.The proportion of T-cell type is also higher than that reported in Japan. Differential diagnosis and several factors which in-fluence immunostaining were also discussed.
【CateGory Index】: R738.1
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