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《Chinese Journal of Medical Ultrasound(Electronic Edition)》 2012-01
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The value of intraoperative contrast-enhanced ultrasonography for improving the completely resection of cerebral gliomas

HE Yan,HE Wen,DU Li-juan,WANG Li-shu,YU Shu-qing,WANG Ji-sheng,LI Hui-zhan.Department of Ultrasound,Beijing Tiantan Hospital Capital University of Medical Sciences,Beijing 100050,China  
Objective To explore the value of conventional ultrasound and contrast-enhanced ultrasonography in intraoperative detection of residual gliomas.Methods Conventional ultrasonography and contrast-enhanced ultrasonography were performed in 38 patients with gliomas intraoperatively,and with real-time observation of tumor resection.The samples resected from the tumor-brain interface which were reported as tumor or normal tissue on intraoperative contrast-enhanced ultrasonography were submitted to pathology.The diagnosis were compared with pathological findings.Results Two hundred and five samples were taken from 38 gliomas cases who were operated with the guidance of intraoperative conventional ultrasonography and contrast-enhanced ultrasonography.Pathological findings showed complete tumor resection in 28 cases(28/38)and residual tumors in 10 cases(10/38).There were 29 true and 9 false diagnosis by intraoperative conventional ultrasonography,coincidence rate between pathology and intraoperative conventional ultrasound diagnosis was 76.3%(29/38).There were 34 true and 4 false diagnosis by intraoperative contrast-enhanced ultrasonography,coincidence rate between pathology and intraoperative contrast-enhanced ultrasound diagnosis was 89.5%(34/38).Coincidence rate of intraoperative contrast-enhanced ultrasound diagnosis of residual tumor was higher than that of conventional ultrasound,with a statistically significant difference(χ2=0.835,P0.01).Conclusion Intraoperative contrast-enhanced ultrasonography can detect the residual tumor effectively,which is beneficial for improving the precision of total resection.
【Fund】: 首都医学发展基金重点资助项目(2005-2025)
【CateGory Index】: R739.4
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【Co-references】
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