Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Trauma》 2005-03
Add to Favorite Get Latest Update

Behavioral assessment of acute suction traumatic brain injury rat model

HU De-zhi, ZHOU Liang-fu, WU Xue-hai. Department of Neurosurgery, Huashan Hospital Affiliated to Fudan University, Shanghai 200040, China Corresponding author: ZHOU Liang-fu  
Objective To assess the behavior of rat by suction traumatic brain injury model. Methods Suction traumatic brain injury (TBI) models were created in SD rats. Twenty-four rats were divided into two groups: suction TBI group (n=12) and sham operation group (n=12). Modified neurological severity score (mNSS) test and Morris water maze test were employed to assess the animal behavior in both groups. Results One rat was died of suction trauma. Success rate of modeling for those survivors was one hundred per cent. Cortical and subcortical contusion, hemorrhage and tissue loss were seen in paraffin section by HE staining one week after suction impact. Abnormal mNSS persisted no more than twenty-five days. Morris water maze test suggested that abnormal mean escape latency period last no more than three days. Conclusion Rat suction traumatic brain injury model is suitable for the research about neurological sensory-motor function which last relatively short period.
【CateGory Index】: R651
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 2 Hits
1 GU Bing1,JIN Jian-bo2,MENG Wei1,LI Hua-nan21College of Life Science,Jiangxi Science & Technology Normal University,Nanchang 330013,Jiangxi,China;2School of Pharmacy,Jiangxi University of Traditional Chinese Medicine,Nanchang 330006,Jiangxi,China;Establishment of traumatic brain injury model in rats[J];Chinese Journal of Clinical Pharmacology and Therapeutics;2010-12
2 LIU Yuan, WANG Li, ZENG Lin, et al . Research Institute of Field Surgery, Chongqing 400042, China;Establishment of Model of Traumatic Brain Injury by an Improved Method in Rats[J];Chinese Journal of Clinical Neurosurgery;2008-07
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LI Hong li, CAI Wen qin, DENG Xiao lin, ZHAO Shi fu (Department of Histology and Embryology, Third Military Medical University, Chongqing 400038, China);Comparative study of NO expressions with different types of brain injury in rats[J];ACTA ACADEMIAE MEDICINE MILITARIS TERTIAE;2000-07
2 LI Zhi-Yong 1, ZHANG Xiang 1, FEI Zhou 1, LIU Xian-Zhen 1, LIANG Jing-Wen 1, LI Shu-He 1, YANG Ji-Qing 2, MA Fu-Cheng 3 1Department of Neurosurgery, Xijing Hospital, 2Department of Physics, Faculty of Biomedical Engineering, 3De;Establishment of the model for brain injury in unanaesthetized and awake rats[J];JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY;2000-07
3 HE Xiao Sheng, ZHANG Xiang, YI Sheng Yu, FEI Zhou, ZHANG Jian Ning, YANG Li Sun Institute of Neurosurgery of Chinese PLA, Xijing Hospital, Fourth Military Medical University, Xi'an 710033, China;Alterations of brainstem-auditory evoked potential in rats with brain diffuse axonal injury[J];JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY;2000-09
4 ZHANG Yong He 1,ZHAO Ning 2,YI Sheng Yu 3, ZHANG Xiang 3 1Department of Emergency Medicine, Xijing Hospital, 2Biotechnology Center, 3Institute of Neurosurgery of Chinese PLA, Xijing Hospital, Fourth Military Medical University, Xi;Injury model of central neuron by air pressure in vitro[J];Journal of The Fourth Military Medical University;2002-05
5 LI Jian Hu, HE Li Sheng, LEI De Lin, ZHANG Ming, TIAN Lei, WANG Xiang, LIU Rui Feng, ZHOU Shu Xia Department of Oral and Maxillofacial Surgery, Stomatological College, Fourth Military Medical University, Xi'an 710033, China;Establishment and study on the discal injury of animal model of blast injury in maxillofacial region[J];Journal of The Fourth Military Medical University;2002-08
6 HUANG Wei Dong, FEI Zhou, ZHANG Xiang, WANG Xi Ling PLA Institute of Neurosurgery , Xijing Hospital, Fourth Military Medical University, Xian 710033, China;Mechanical injury model of cortical neuron of rat in vitro[J];Journal of The Fourth Military Medical University;2004-04
7 ZHENG Chun-Xia, JIN Wei-Lin, JU Gong Institute of Neuroscience, Fourth Military Medical University, Xi’an 710033, China;Investigation of expressional change and function of Nogo-A in neurons after oxidative stress[J];Journal of The Fourth Military Medical University;2004-19
8 Yu Xiao jun, et al. (Department of forensic medicine, JiLin medical College 132001);Experiment study on early pathological changes of closed diffuse craniocerebral injury[J];The Journal of Law and Medicine;1998-02
9 Chen Xi-ping, Tao Lu-yang, China Medical University, School of Forensic Medicine. Shenyang. 110001 P.R.China.;Lognitudinal study of of ABR In Patients with Mild Head Injury[J];The Journal of Law and Medicine;2002-02
10 Yao Fengsheng,et al. Kunming,Medical College,650031;AN EXPERIMENTAL MODEL OF CEREBRAL CONCUSSION GUINEA, PIG AND THE MORPHOLOGICAL CHANGES[J];Chinese Journal of Forensic Medicine;1992-01
【Secondary References】
Chinese Journal Full-text Database 8 Hits
1 WANG Liang,TANG Wen-yuan,YANG Gang,et al.(Department of Neurosurgery,First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China);Effect of hyperglycemia on the expression of glucose transporter 3 in rats following traumatic brain injury[J];Chongqing Medicine;2010-12
2 Deng Chongdi1,Ma Yi1,Li Jianguo1,Ling Li1,Liu Yang1,Lv Zhongrong2(1.Department of Emergency;2.Operation Room,Affiliated Hospital of Zunyi Medical College,Zunyi,Guizhou 563003,China);The mechanism of sodium selenite and hyperbaric oxygen on the therapeutic effect of traumatic brain injury rats model[J];Chongqing Medicine;2013-11
3 GU Bing1,JIN Jian-bo2,LI Hua-nan2,WANG Shuo-yu2 1School of Pharmacy,Jiangxi Science & Technology Normal University,Nanchang 330013,Jiangxi,China;2School of Pharmacy,Jiangxi University of Traditional Chinese Medicine,Nanchang 330006,Jiangxi,China;Establishment of traumatic spinal cord injury model in rats[J];Chinese Journal of Clinical Pharmacology and Therapeutics;2011-07
4 MIAO Jing-kun,CHEN Qi-xiong,WU Xiao-mei,LIU Zhen-qiu,ZHANG Xiao-ping Department of Neonatology,the Children's Hospital,Chongqing Medical University,Ministry of Education Key Laboratory of Child Development and Disorders,Key Laboratory of Pediatrics in Chongqing,Chongqing International Science and Technology Cooperation Center for Child Development and Disorders,Chongqing 400014,China;Effects of compound decotion on activity and expression of nitric oxide and neuronal nitric oxide synthase in the brain of traumatic brain injury rat model[J];Chinese Journal of Clinical Pharmacology and Therapeutics;2011-12
5 YAO Yanpeng,ZHANG Xinding,HAN Yanming,et al. Department of Neurosurgery,Second Clinical Hospital of Lanzhou University,Lanzhou,730000;The effects of hyperbaric oxygen therapy on neuron apoptosis and apoptosis-related genes after traumatic brain injury in rats[J];Chinese Journal of Rehabilitation Medicine;2011-02
6 WANG Liang,et al (Department of Neurosurgery,the First Affiliated Hospital,Chongqing Medical University);The damage of hyperglycemia to the neurons following traumatic brain injury[J];Journal of Chongqing Medical University;2010-09
7 WANG Liang,TANG Wenyuan,SUNG Xiaochuan,DENG Luping,LI Dong. Department of Neurosurgery,First Affiliated Hospital,Chongqing Medical University,1 Yixueyuan Road,Chonqing 400016,China.;The effect of hyperglycemia on the expression of glucose transporter 1 in rats following traumatic brain injury[J];Chinese Journal of Nervous and Mental Diseases;2010-01
8 WANG Liang,CHENG Liang,LI Dong,TANG Wenyuan.Department of Neurosurgery,First Affiliated Hospital,Chongqing Medical University,1 Yixueyuan Road,Chonqing 400016,China.;The influence of hyperglycemia on the neurons following traumatic brain injury.[J];Chinese Journal of Nervous and Mental Diseases;2010-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved