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Ultrasound-guided ablation therapies for hepatocellular carcinoma: a comparison between microwave and radiofrequency

LU Mingde,XIE Xiaoyan,CHEN Junwei,et al.Department of Hepatobiliary Surgery,the First Affiliated Hospital,Sun Yat Sen University of Medical Sciences,Guangzhou 510080,China  
Objective Comparing the value in clinical practice of ultrasound guided ablation therapies for liver cancer between using microwave and using radiofrequency.Methods From August,1997 to March,2000,percutaneous microwave coagulation therapy(PMCT) was employed to treat 67 cases of liver cancer with 141 nodules,with a diameter of 0.8 ~ 6.4 cm[( 2.5 ± 1.1 ) cm];and from February,2000 to January,2001,percutaneous radiofrequency(PRF) was used to treat 23 cases of liver cancer with 41 nodules,with a diameter of 0.7 ~ 5.0 cm[( 2.5 ± 1.0 ) cm].Summarizing the results of the above stated two clinical researches,a preliminary comparison between PMCT and PRF in local ablation effect and invasiveness was made.Results The tumor completely ablation rate was 90.1% (127/141) in PMCT and 87.8% (36/41) in PRF,which showed no significant difference in statistics(χ 2= 0.17 ,P= 0.68 ).There was also no difference in side effect and complication between the two ablation techniques.Conclusions Both PMCT and PRF are contemporary ideal therapeutic approaches of interventional ultrasound for HCC.PMCT is low cost and easy to be accepted.A high cost may represent the major disadvantage of PRF,which may limit its extensive application in our country.
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