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《Chinese Journal of Ultrasonography》 2003-02
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Differential diagnosis of hepatic tumors with dynamic grey-scale enhanced ultrasonography

WANG Wen-ping, DING Hong, QI Qing, et al. Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
Objective To evaluate the value of dynamic grey-scale enhanced ultrasonography in the differential diagnosis of hepatic tumors.Methods Twenty-four patients with 25 hepatic solid lesions were examined by dynamic enhanced ultrasonography with a bolus injection of Levovist (400 mg/ml). Results All lesions were confirmed by operation and pathology, including 16 hepatocellular carcinomas (HCC), 3 hepatic hemangiomas (HCH), 1 inflammatory pseudotumor of liver (IPL), 2 focal nodular hyperplasias (FNH) and 3 angiomyolipomas (AML). Twenty-five lesions were variously enhanced on grey-scale ultrasonogram after injection of Levovist except for IPL. The lesions with HCCs were enhanced early in the arterial phase and disappeared quickly in portal phase. The lesions with HCHs were enhanced slowly in the peripheral region of the lesion. The FNH and AML were also enhanced early in arterial phase, but disappeared slowly in delay phase. If the hepatic lesions showed the earlier enhancement in arterial phase and fast disappearance in portal phase on contrast enhanced ultrasonogram were regarded as a criterion of malignant tumor, the sensitivity, specificity and accuracy with contrast enhanced ultrasonography in the diagnosis of hepatic malignant tumor were 94%(15/16),89%(8/9)and 92%(23/25), respectively. Conclusions The dynamic grey-scale enhanced ultrasonography is a useful technique in the differential diagnosis of hepatic tumors.
【Fund】: 上海市教委科研基金资助 ( 2 0 0 0QN0 9)
【CateGory Index】: R735.7
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