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《Chinese Journal of Radiology》 2000-12
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The pulmonary artery doesn′t participate in the blood supply of lung cancer: experimental and DSA study

HAN Mingjun *, FENG Gansheng, YANG Jianyong, et al. * Department of Radiology, First Hospital, China Medical University, Shenyang 110001, China  
Objective To investigate whether or not the pulmonary artery participates in the blood supply of lung cancer and its change of morphology and blood flow in lung cancer. Methods Two different colors of silicone were injected separately into the bronchial and pulmonary arteries of 33 rat models with squamous cell carcinoma of lung. The origin of blood supply of lung cancer and the morphologic change of pulmonary artery were observed under a stereomicroscope. The DSA of bronchial and pulmonary artery were performed simultaneously in 28 patients with lung cancer. Results The pulmonary branch of rat and patients were reduced, thinned and occluded in the affected lung. The pulmonary artery did not form tumor vessel, and pulmonary blood flow and perfusion were reduced or absent in the affected area. Conclusion The pulmonary artery didn′t participate in the blood supply of lung cancer. It is unreasonable to perform transcatheter chemo embolization for lung cancer via pulmonary arteriay.
【Fund】: 国家“九五”攻关课题资助项目 !(96 90 7 0 3 0 3)
【CateGory Index】: R734.2
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