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《Chinese Journal of Radiology》 2005-07
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A study of whole brain perfusion CT and CT angiography in hyperacute and acute cerebral infarction

ZHANG Yong-hai,BAI Jun-hu,ZHANG Ming,YANG Guo-cai,TANG Gui-bo,FANG Jun,SHI Wei,LI Xing-hua,LIU Su-ping,LU Qing,TANG Jun. Department of Radiology, Qinghai Provincial People′s Hospital,Xining 810007,China  
Objective To evaluate the diagnostic value of whole-brain perfusion blood volume-weighted CT imaging (PWCT) and simultaneous CT angiography (CTA) on early stage of cerebral ischemic infarction. Methods Non-contrast CT (NCCT), CT perfusion-weighted imaging (PWCT) and delayed CT (DCT) were conducted on 20 cases of early ischemic infarction of whose onset time ranged from 2 to 24 hours. All cases were reexamined with CT or MRI one week to one month later. CT values and perfusion blood volume (PBV) of central and peripheral low perfusion areas as well as those of collateral side were measured. CTA was reconstructed with PWCT as source images to evaluate occlusion or stenosis of blood vessel, and DCT was used to detect the collateral circulation. Results Of the 20 cases, NCCT, PWCT and CTA were negative in 10 cases in which 6 were confirmed as Transient Ischemic Attack (TIA) on reexamined CT and clinical features, and the other 4 were confirmed as lacunar infarction. For the remaining 10 cases, a comparison was made with ANOVA between low perfusion area (central, peripheral inside and outside) and collateral side. The difference was significant (P0.01). However, no significant difference was revealed in the central, peripheral inside and outside areas. PBV values were significant in low perfusion area and collateral side (P0.05). The area of the final infarction was larger than that of the low perfusion area, and the percentage of enlargement exhibited medium negative correlation to the time of ischemia. CTA indicated that 2 cases suffered from left middle cerebral artery occlusion, meanwhile anterior and middle branches of MCA in the other 3 cases were not identified. The sensitivity of NCCT, PWCT and CTA were 28.5%, 71.4% and 35.7% respectively. DCT indicated that 5 cases had asymmetrical blood vessels. Conclusion The whole-brain perfusion-weighted CT imaging and simultaneous CT angiography (CTA) is proved to be a simple, timesaving and effective method for the diagnosis of early stage of ischemic infarction. This method can identify the existence, size, location and corresponding blood-supplying arteries of low perfusion area. It can also predict the existence of ischemic penumbra, providing semi-quantitative and morphological evidence for the clinical treatment of thrombolysis.
【CateGory Index】: R743.3
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Chinese Journal Full-text Database 8 Hits
1 ZHOU Zhipeng,DENG Yanxian, QIU Weijia,et al.Department of Radiology,Affiliated Hospital of Guilin Medical College 541001,P.R.China;The DSA and CT Perfusion Evaluation of New Model of Artery Occlusion in Monkey[J];Journal of Clinical Radiology;2008-11
2 MAN Xiao,LENG Zhen-pu,PANG Zai-ying,DU Yi-feng (Department of Neurology,Provincial Hospital Affiliated to Shandong University,Jinan 250021,China);CT perfusion imaging and determination of Glu and GABA content in acute cerebral infarction[J];Journal of Shandong University(Health Sciences);2008-08
3 LIU Xiao-dong,YAO Xiao-ping,XIE Wen-xia,et al.Department of Radiology,Workers General Hospital of Tongling Nonferrous Metals Group,Tongling 244000,Anhui,China;Comparative Study on Quantitative CT Values of Fresh and Olden Lacunar Cerebral Infarction[J];Chinese Journal of General Practice;2010-02
4 ;Clinical and imagic analysis of acute cerebral vascular disease with onset of seizure[J];Journal of Medical Imaging;2005-11
5 YAO Zhen-wei ZHANG Fang FENG Xiao-yuan Department of Radiology.Huashan Hospitar,Fudan University;Evaluation of Rabbit Cerebral Mini-embolic Ischemia Model with CT Perfusion[J];Chinese Computed Medical Imaging;2008-04
6 YU Qin,RAN Long-fu;CT diagnosis advancement of acute cerebral infarction[J];Practical Journal of Clinical Medicine;2009-01
7 JIANG Bao-dong* FENG Xiao-yuan LIU Cheng LI Ke YU Fu-hua *Department of Radiology,Huashan Hospital,Fudan University,Shanghai 200040,China;Study on imaging parameters of multi-slice spiral CT long coverage angiography in intracranial and cervical arteries[J];Chinese Journal of Radiology;2006-09
8 HE Wen-juan,SHEN Jia-lin,XU Jian-rong,HUA Xiao-lan(Department of Radiology,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China);Diagnosis of cerebrovascular diseases with 128-detector CT[J];Chinese Journal of Medical Imaging Technology;2011-01
Chinese Journal Full-text Database 3 Hits
1 Chen Xingrong; Shen Tianzhen (Department of Radiology, Huashan Hospital, Shanghai Medical University, Shanghai 200040);Imaging of Cerebral Infarct[J];CHINESE JOURNAL OF MEDICAL COMPUTED IMAGING;2000-01
2 LU Jie, LI Kuncheng, DU Xiangying Department of Radiology, Xuanwu Hospital, the Capital Medical University, Beijing 100053, China;The preliminary study of CT cerebral perfusion imaging in transient ischemic attacks[J];Chinese Journal of Radiology;2002-04
3 GUAN Xiaoting *,LIU Xiang, LONG Jie, et al. *Department of Neurology,Beijing Tiantan Hospital,Beijing 100050,China;CT perfusion imaging and CT subtraction angiography in diagnosing acute ischemic cerebrovascular disease[J];Chinese Journal of Neurology;2000-05
Chinese Journal Full-text Database 10 Hits
1 HAN Hui, WU Li-min, TU Jin-wen, HAN Ming-xiang (Hubei Chinese Medical College, Wuhan 430061,China);Studying the effect of shenxiongqin injection in reducing the content of ET-1,TNF-α,IL-1β of focal cerebral infarction in rats[J];Anhui Medical and Pharmaceutical Journal;2005-01
2 SHI Chuan-ying,DONG Liu-yi(Department of Pharmacology,Anhui Medical University,Hefei 230032,China);Effects of xuesaitong injection on cerebral blood flow in anaesthesia dogs and experimental thrombosis in rats and thrombolysis in rabbits[J];Anhui Medical and Pharmaceutical Journal;2009-04
3 LUO Zhong-da Tutor: Professor LAI Xin-sheng,Doctor XU Neng-gui (Futian Hospital of Traditional Chinese Medicine of Shenzhen City,Guangdong Shenzhen 518034,China);EFFECT OF ELECTRO-ACUPUNCTURING DU CHANNEL ON NEUROCYTE APOPTOSIS IN ISCHEMIC CEREBRAL INJURY RATS[J];Journal of Anhui Traditional Chinese Medical College;2002-06
4 HAN Hui,WU Li-min,WANG Mei-xia,YANG Bo,WANG Han,TU Jin-wen,HAN Ming-xiang(The First Hospital Affiliated to Anhui College of Traditional Chinese Medicine,Anhui Hefei 230031,China);Effects of Renshen Chuanxiongqin Injection on t-PA Concentration and Its Activity,PAI-1 Concentration and Histomorphological Changes in Rats with Focal Cerebral Ischemia[J];Journal of Anhui Traditional Chinese Medical College;2008-06
5 QIAN Wei dong (Department of Neurology,Affiliated Hospital of Bengbu Medical College,Anhui 233004,China);MRA in diagnosis of Moyamoya disease:A report of 10 cases[J];Journal of Bengbu Medical College;2003-04
6 LI Rong-yuan1,WANG An-li2 (1.College of Physical Education and Health Science,Guangxi University for Nationality,Nanning 530006,Guangxi China;2.Beijing Sport University,Beijing 100084,China);Effects of Kinetotherapy Supplemented by Early Massage on Diabetic Patients with Stroke[J];Journal of Beijing Sport University;2009-01
7 ZHOU Juan 1 , ZHANG Min 1 , LI Xiaoming 21 Faculty of Chinese Traditional Medicine, First Military Medical University, Guangzhou 510515, China; 2 Department of Chinese Traditional Medicine, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China;The determination of serum lipids and serum lipoprotein electrophoretagram in patients with cerebrovascular diseases[J];Chinese Journal of Neuromedicine;2003-01
8 YANG Yingming Department of Neurosurgery, First Affiliated Hospital, Shantou University Medical College, Shantou 515041, China;The pathopoiesia characteristic and surgical countermeasures of hypertensive hematoma[J];Chinese Journal of Neuromedicine;2003-03
9 ZHAO Jianping, SHI Qingping, REN Hairong, DU Liping, QU Chengyi Department of Neurology, Second People's Hospital, Jinzhong 030800, China; Public Health College, Shanxi Medical University, Taiyuan 030001, China;Perilous factors of intracerebral hemorrhage[J];Chinese Journal of Neuromedicine;2004-01
10 YANG Yu-hua~* SHI Hao ZHU Cui-ling. *Shandong Provincial Center for Disease Control and Prevention,Ji'nan 250014,China;A building and evaluation of regression equation for magnetic resonance imaging diagnosis following pre-infarction cerebral perfusion[J];Chinese Journal of Neuromedicine;2006-08
China Proceedings of conference Full-text Database 1 Hits
1 ZHANG Hai-feng (Dept.of Acu-moxibustion of Zhejiang hospital of TCM,Hangzhou 310006,Zhejiang,China.);Effect of scalp Acupuncture on TGF-β1 Expression in Cerebral Ischemia Rats[A];[C];2009
Chinese Journal Full-text Database 10 Hits
1 ZHOU Wu1,2, SHU Xiao-Chun3, WANG Xue-Qing2, LIU Han-Wei2, HAN Rong-Rong2, ZHANG Su-Ming11Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China, 2Department of Neurology, 3Department of Endocrine, The 5th Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China;Influence of anti-platelet therapy on the expressions of platelet activation markers in patients with acute cerebral infarction[J];Journal of the Fourth Military Medical University;2007-05
2 QIU Qian-de,XU Jia-jun,LIU Xu-ming,et al.Department of Radiology,the Third People′s Hospital of Wenzhou,Zhejiang 325000,P.R.China.;Evalution of DWI Combined with ADC Mapping in the Diagnosis of Acute Cerebral Infarction[J];Radiologic Practice;2006-02
3 YANG Bin,WU Zui-xin,YU Yi-xin,et al.Department of Radiology,Hangzhou the First Hospital,Hangzhou 310006,P.R.China;Evaluation of Ischemic Cerebrovascular Disease with CT Angiography of Head and Neck[J];Radiologic Practice;2007-10
4 ZHOU Zhi-peng,QIU Wei-jia,ZHANG Hui-yang,et al.Department of Radiology,The Affiliated Hospital of Guilin Medical College,Guilin 541001,China;Identification of the penumbra and infarct core on noncontrast CT scan[J];Acta Medicinae Sinica;2008-05
5 LIU Yong-sheng(Hospital,Tsinghua University,Beijing 100084,China);An Analysis on CT Imaging Features of Lacunar Infarction and the Clinical Features in 175 Cases[J];Health Medicine Research and Practice;2009-02
6 DU Wei, SHAO Cheng min, WANG Jian lin, et al. Department of Radiology, The Second Yunnan Provincial People's Hospital, Kunming 650021, China;Intra-artery thrombolytic therapy for acute ischemic cerebral infarction[J];Journal of Interventional Radiology;2004-03
7 YANG Rui-min, ZHANG Ming-qiu~*, ZHAO Dong-ju, LI Fen-bao, YAO Wei-hua, ZHAO Peng, LIU Ai-guang (Imaging and Interventional Centre, the First Affiliated Hospital of Xinxiang Medical College, Weihui 453100, China);Analysis of therapeutic time window and effect in acute cerebral infarction treated with intra-arterial thrombolytic therapy[J];Chinese Journal of Interventional Imaging and Therapy;2006-01
8 ZHANG Quan, SUN Junmo, TIAN Zhixiong,et al. Medical Imaging Center, Zhongnan Hospital, Wuhan University, Wuhan, Hubei Province 430071, P.R.China;Study on Hyperacute Cerebral Infarction and Reperfusion in Rat with Diffusion Weighted Magnetic Resonance Imaging[J];Journal of Clinical Radilolgy;2001-06
9 YIN Xindao *, FENG Xiaoyuan, WANG Liping, et al. *Department of Radiology, The Affiliated No.1 Hospital, Nanjing Medical University, Nanjing, Jiangsu Province 210006, P. R. China;Diffusion-Perfusion MR Imaging of Hyperacute Cerebral Infarction Penumbra: An Experiment in Rats[J];Journal of Clinical Radiololgy;2004-03
10 CHEN Weiwei, QI Jianpin, SONG Jinmei,et al. Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province 430030, P. R. China;The Relationship between the Change of Blood Flow and the Probability of Infarct in the Embolic Model of Cerebral Ischemia[J];Journal of Clinical Radiololgy;2005-07
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 WANG Bin,FU Qiang,XU Kai-yuan,et al.Department of Radiology,Dongguan Kanghua Hospital,Guangdong 523080,P.R.China;Study of 64-slice Spiral CT Techniques in Cerebral and Carotid CT Arteriography[J];Radiologic Practice;2009-01
2 ZHOU Jun,LONG Qingyun,LIU Junfang,HU Jinxiang,LIU XinxianDept.of Radiology,Zhongnan Hospital of Wuhan University,Wuhan 430071,China;Changes of CT Perfusion Imaging of Rabbit Bearing VX2 Hepatoma After Interventional Treatment[J];Medical Journal of Wuhan University;2010-03
3 LI Chuanming,WANG Jian,DAI Mingde,et al.Department of Radiology,the First Affiliated Hospital to the Third Military Medical University,Chongqing 400038,China;Dual-source CT angiography technique and its clinic application in cerebral vessels examination[J];Journal of Chinese Practical Diagnosis and Therapy;2010-06
4 ZHONG Jing-song1,SHEN Hai-lin2,DING Yi2,LIN Qian-zao1,XIA Xue-ping1,WANG Hong1,LI Hui1,YANG Yi-long1(1.Huaian Second Hospital,Huaian Jiangsu 223002,China;2.Department of Imaging,the First Affiliated Hospital of Soochow University,Suzhou Jiangsu 215006,China);64-MSCT long coverage angiography of intracranial and cervical arteries in TIA[J];Journal of China Clinic Medical Imaging;2010-07
5 JIANG Bao-dong1,MA Xiang-xing2,WANG Qing2,WANG Qian2,FENG Xiao-yuan1,LI Ke1,YU Fu-hua2(1.Department of Radiology,Huashan Hospital of Fudan University,Shanghai 200040,China;2.Department of Radiology,Qilu Hospital of Shandong University,Jinan 250012, China);Delay time and slile thickness of CT venography of cerebral veins[J];Journal of Shandong University(Health Sciences);2008-11
6 CAI Wu,GONG Jian-ping,ZHU Jiang-tao,QIAO Fang,CHEN Guang-qiang,ZHANG Bo,YI Bi-xing,QIAN Ming-hui (Dept of Radiology,the Second Hospital Affiliated to Soochow University,Jiangsu Suzhou 215004,China);Preliminary Study of the Scan-delay-time During the Combined Examation of CT Perfusion and CT Angiography After Contrast Media Administration in Cerebral and Cervical CT Angiography[J];Suzhou University Journal of Medical Science;2010-02
7 ;Study on the application value of manual triggering technology in coronary-artery CTA[J];Journal of Medical Imaging;2011-04
8 YAN Zhong-yu,WANG Zhen-chang,LIU Zhong-lin;Elementary Application of 16-slice Spiral CT Angiography in Extracranial Carotid and Vertebral Artery[J];Chinese Computed Medical Imaging;2007-06
9 YANG Xian-feng,ZHU Bin,ZHOU Zheng-yang,SONG Wei-tong,DOU Xin,HU An-ning Department of Radiology,Nanjing Gulou Hospital,Affiliated to Nanjing University Medical School 321 Zhongshan Rd., Nanjing 210008,P.R.C.;Bolus-triggered MSCT Angiography in Depicting Intracranial Artery Aneurysm[J];Chinese Computed Medical Imaging;2010-01
10 YANG Jie, ZHANG Jing, HUANG Jie,LI Xiao-long (General hospital of PLA, Beijing 100853, China);Study on Imaging Quality of 64-Slice Spiral CT Long Coverage Angiography in Intracranial and Cervical Arteries[J];Chinese Medical Equipment Journal;2008-10
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 WANG Baojun; LI Meilin; WANG Gianli et al . (Department of Neurology' theThird Hospital, Beijing Medijing Medical University,Beijing 100083);The value of diffusion-weighted and perfusion-weighted MRI in the diagnosis of acute ischemic cerebrovascular disease[J];CHINESE JOURNAL OF NEUROLOGY;1999-05
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