Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Radiology》 2007-10
Add to Favorite Get Latest Update

A study on the application of CT perfusion and CT angiography with 64-slice spiral CT in the evaluation of internal carotid artery and middle cerebral artery stenosis and occlusion

GAO Yan LI Kun-cheng DU Xiang-ying LU Jie LIU Jia-bin YANG Yan-hui SHEN Yun Department of Radiology,Xuanwu Hospital,Capital Medical University,Beijing 100053,China  
Objective To evaluate clinical application of combined cerebral CT perfusion(CTP) with head and neck CT angiography(CTA)using 64-slice spiral CT on the cerebral ischemia caused by the stenosis or occlusion of internal carotid artery(ICA)and middle cerebral artery(MCA).Methods The sixty nine patients with unilateral or bilateral ICA and MCA stenosis or occlusion confirmed by digital subtraction angiography underwent head plain CT scan,cerebral CTP,and head and neck CTA using 64-slice spiral CT.Ten normal adults served as control.To discriminate the ischemie foci,the parameter maps of cerebral blood flow(CBF),cerebral blood volume(CBV),mean transit time(MTT)and time to peak(TTP)were obtained.Results Among the patients with unilateral ICA stenosis or occlusion diagnosed by CTA,abnormal perfusion was found only in the watershed zone in 5 cases,both the MCA territory and the watershed zone were involved in 10 cases.Of 12 patients with severe unilateral ICA stenosis and occlusion, CBF values of the watershed zone in nonsymptmatic and symptomatic sides were(41±9)and(38±8)ml· 100 g~(-1),min~(-1)respectively(t=2.08,P0.05),the MTT values were(5.2±1.1)and(10.9±2.6)s, respectively(t=7.24,P0.01).Thirteen patients with severe bilateral ICA stenosis or occlusion diagnosed by CTA had perfusion abnormalities in the both the MCA territory and the watershed zone.Of 25 patients with unilateral MCA stenosis,4 patients were normal in CT perfusion,17 patients had perfusion abnormalities in MCA territory,and 4 patients had perfusion abnormalities in both MCA territory and the watershed zone.Twelve patients with severe bilateral MCA stenosis diagnosed by CTA had perfusion abnormalities in both the MCA territory arid the watershed zone.Compared to normal control,the MTT and TTP were increased,the CBF was decreased,and the CBV in MCA territory and the watershed zone at the symptomatic side was increased.Conclusion The combined examination of CTP with CTA can provide adequate and accurate information for the diagnosis and treatment of middle cerebral artery and internal carotid artery stenosis or occlusion.
【CateGory Index】: R816.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 LI Ping,ZHANG Zai-ren,ZHAO Yan-ming,WANG Hui,JIANG Hui-jie,ZHAO De-li,LI Yong-li(Department of Radiology,2nd Hospital of Harbin Medical University,Harbin 150086,China);The Study of CT Perfusion and CT Angiography in the Stenosis of Internal Carotid Artery with Transient Ischemic Attacks[J];Journal of Practical Radiology;2009-08
【Citations】
Chinese Journal Full-text Database 2 Hits
1 JIAO Li-qun, LING Feng, MIAO Zhong-rong,ZHANG Hong-qi,JI Xun-ming,DONG Bai-jing,SONG Qing-bin,ZHANG Yang(Department of Interventional Neurosurgery, Xuanwu Hospital of CapitalUniversity of Medical Science, Beijing 100053,China);Morphologic and Hemodynamic Evaluation of Middle Cerebral Artery Stenoses or Occlusion[J];Journal of Practical Radiology;2005-02
2 LIU Xiang, DAI Jian-ping, ZHAN Jiong, SUN Bo. Department of Neuroradiology, Beijing Neurosurgical Institute, Beijing 100050, China;The application study of CT perfusion and CT subtraction angiography in the stenosis and obstruction of internal carotid artery[J];Chinese Journal of Radiology;2003-08
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 DAI Weiying,JIN Song,TIAN Chao,YAN Shixin. Department of Radiology, Tianjin Huanhu Hospital, Tianjin 300060, China;The clinical application of 64-slice spiral CT angiography in carotid artery bifurcation disease[J];International Journal of Medical Radiology;2008-06
2 Yang Xuehua,Tan Yanzhao,Gao Jianbo,et al.Department of Radiology,the First Affiliated Hospital of Zhengzhou Medical University,Zhengzhou 450052,China;The evaluation of 64 multi-slice spiral CT angiography in the diagnosis of cerebral and carotid artery diseases[J];Chinese Journal of Practical Nervous Diseases;2008-09
3 LI Mingli, JIN Zhengyu, ZHANG Yunqing,et al.Department of Radiology, Peking Union Medical College Hospital, Chinese Acadamy ofMedical Sciences & Peking Union Medical College, Beijing 100730, P. R. China;Feasibility of Multislice CT Angiography with Low Dose Contrast Media in the Head and Neck[J];Journal of Clinical Radiololgy;2005-03
4 CHU Jianping, YANG Jianyong, CHEN WeiRadiology Department of the First Affiliated Hospital of Sun-yat Sen University, Guangzhou, Guangdong Province 510080,P.R.China;Combination of Cerebral CT Perfusion and CT Angiography in the Evaluation of Acute Cerebral Infarction and Carotid Artery Stenosis[J];Journal of Clinical Radiology;2008-04
5 WANG Liping, ZHAO Chunyu, LI Shuyan Department of CT,The First Hospital of Harbin Medical University,Harbin,Heilongjiang Province 150001,P.R.China;The Multislice CT Evaluation of Carotid Artery Stenosis in Patients with TIA[J];Journal of Clinical Radiology;2008-09
6 WU Zong-xia, LEI Zhen, QIAN Ying, WANG Zhi-ming(Department of Radiology, the First Affiliated Hospital of Liaoning Medical College, Jinzhou Liaoning 121001, China);The feasibility study of MSCT angiography with low dose contrast media in the carotid artery:a canine experimental model[J];Journal of China Clinic Medical Imaging;2009-04
7 WU Xing-you,et al.(The First People's Hosp.of Yinchuan,Yinchuan 750001,China);Clinical application of multi-section spiral CT angiography in carotid arteriosclerosis with:report of 20 cases[J];Ningxia Medical Journal;2008-02
8 He Jie1,Ji Xunming2,Zhang Renling1,Zhai Yong1,Guan Yue1,Xu Yinglu1(1.Department of Nuclear Medicine,Xuanwu Hospital,Capital Medical University;2.Department of Neurosurgery,Xuanwu Hospital,Capital Medical University);Study on the Relation between Collateral Circulation and Cerebral Ischemia in Patients with Unilateral Middle Cerebral Artery Stenosis or Occlusion[J];Journal of Capital Medical University;2008-01
9 JIN Guan-qiao,SU Dan-ke,ZHU Xiao-dong,XIE Dong,HUANG Chen-yang(CT Department,the Affiliated Tumor Hospital of Guangxi Madical University,Nanning 530021,China);The Primary Study of Multi-slice Helical CT Perfusion in Nasopharyngeal Carcinoma[J];Journal of Practical Radiology;2005-10
10 CAO Xin-shan,ZHAO Jian-nong,QIN Dong-jing,ZENG yan,YU Cong,LUO Yin-deng(Department of Radiology,the Second Hospital of Chongqing Medical University,Chongqing 400010,China);Clinical Application of 16-slice Spiral CT Angiography in Internal Carotid Artery[J];Journal of Practical Radiology;2007-05
【Co-references】
Chinese Journal Full-text Database 3 Hits
1 CHU Jianping, YANG Jianyong, CHEN WeiRadiology Department of the First Affiliated Hospital of Sun-yat Sen University, Guangzhou, Guangdong Province 510080,P.R.China;Combination of Cerebral CT Perfusion and CT Angiography in the Evaluation of Acute Cerebral Infarction and Carotid Artery Stenosis[J];Journal of Clinical Radiology;2008-04
2 LU Jie LI Kun-cheng ZHANG Miao(Department of Radiology,Xuanwu Hospital,Capital University of Medical Science,Beijing 100053,China);The application of 64 multislice spiral CT cerebral perfusion imaging and CT angiography in patients with TIA[J];Chinese Journal of Geriatric Heart Brain and Vessel Diseases;2006-12
3 LU Jie, LI Kuncheng, DU Xiangying Department of Radiology, Xuanwu Hospital, the Capital Medical University, Beijing 100053, China;The preliminary study of CT cerebral perfusion imaging in transient ischemic attacks[J];Chinese Journal of Radiology;2002-04
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 LU Xiaoyan, ZHANG Wanshi, XU Jiaxing, et al. Department of CT and MRI, Air Force General Hospital of PLA, Beijing 100036,China;The application of MR and CT angiography in the evaluation of carotid artery stenosis and follow up of carotid endarterectomy[J];Chinese Journal of Radiology;2001-05
2 LIU Xiang, DAI Jianping, SUN Bo, et al Department of Neuroradiology, Beijing Neurosurgical Institute, Beijing 100050;The preliminary research of CT perfusion imaging in intraaxial ischemic disease[J];CHINESE JOURNAL OF RADIOLOGY;1999-07
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved