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《Chinese Journal of Nautical Medicine》 2001-04
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Effect of rhubarb and 5-fluorouracil in the treatment of 34 cases of acute pancreatitis

MAO Xin, HUANG Wenyue, L Jiao, et al. Department of Gastroenterology, No.411 Hospital of CPLA, Shanghai 200081  
Objective To study the efficacy and therapeutic mechanism of rhubarb and 5-fluorouracil(5-Fu) in the treatment of acute pancreatitis. Methods Thirty-four patients with acute pancreatitis(5 severe) were treated with both rhubarb and 5-Fu. The changes of clinical symptom and blood WBC, amylase, ALT,BILIT,LDH, glucose and PaO 2 at the time of 0,24,48,72 h after admission were observed. Results The markedly effective rate and total effective rate of the 34 treated cases were 74% and 88% respectively, and for the mild and moderate cases, they were 86% and 100%. Conclusions Rhubarb and 5-Fu together could improve clinical symptom and mircrocirculation, reduce WBC and inhibit inflammatory mediator in patients with acute pancreatitis significantly; besides, they are of low cost related to their high therapeutic effect.
【CateGory Index】: R835.2
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