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《CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES》 1999-09
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A preliminary study on the markers of pulmonary vascular endothelial cells in patients with ARDS

LI Qi, QIAN Guisheng, CHEN Zhengtang,et al Institute of Respiratory Diseases, Xingqiao Hospital, Third Military Medical University, Chongqing, 400037  
Objective To explore the changes of the markers of pulmonary vascular endothelial cell(PVEC) in patients with ARDS Methods The levels of plasma circulating endothelial cell(CEC), granule membrane protein 140(GMP 140), endothelin 1(ET 1) and von Willebrand factor (vWF) were determined respectively in 13cases of ARDS The vWF on the surface of the PVEC were stained in 5cases of ARDS Results Circulating CEC,GMP 140, ET 1 and vWF levels were increased significantly ( P 0 01) but scores of vWF expression on the PVEC became weak ( P 0 01) in ARDS samples The level of plasma GMP 140 elevated dramatically in 2nd day(4 times) Conclusions PVEC are severely impaired during ARDS GMP 140 released from PVEC might be a satisfactory criteria for early surveillance and for evaluation of prognosis of ARDS in clinical practice
【Fund】: 军队九五重点课题基金
【CateGory Index】: R563.8
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【Co-references】
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1 PENG Wen-hong,MAO Bao-ling,ZOU Xia-ying,WANG Ping;The protective effects of ACEI on the vascularendothelium in hypoxic pulmonary hypertension rats[J];中国病理生理杂志;2003-07
2 LI Wengui CHEN Yatang LIU Chengwei (Institute of Infectious and Parasitic Diseases,The First Affiliated Hospital,Chongqing Medical University,Chongqing 400016);Effects of dihydroartemisinin on apoptosis of spleen cells in rats infected with Pneumocystis carinii pneumonia[J];中国人兽共患病杂志;2003-02
3 JIN Hui ling,ZHANG Ru zhi,GAO Yu xiang,TANG Su lan (Department of Dermatology,Affiliated Hospital of Bengbu Medical College,Bengbu 233004,China);THE STUDY OF ANTIBATERIAL AND ANTIFUNGAL ROLE OF ARTESUNATE[J];中国微生态学杂志;2003-01
4 XING Yinghong,CAO Shuhua,CUI Keliang,LI Jian,WANG Chinta.ICU,First Central Hospital of Tianjin,Tianjin 300192,China;Significance of soluble P-selectin and thrombomodulin in early diagnosis of multiple organ dysfunction syndrome[J];中国危重病急救医学;2002-08
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6 LI Qi, QIAN Guisheng, CHEN Zhengtang,et al Institute of Respiratory Diseases, Xingqiao Hospital, Third Military Medical University, Chongqing, 400037;A preliminary study on the markers of pulmonary vascular endothelial cells in patients with ARDS[J];中华结核和呼吸杂志;1999-09
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