Efficacy of Omeprazole Combined with Famotidine in the Treatment of Duodenal Ulcer
SHI Fei-peng;Zengkou Central Health Center,Bazhou District,Bazhong City,Sichuan Province;
Objective To study the effect of omeprazole combined with famotidine in the treatment of duodenal ulcer. Methods The patients with duodenal ulcer were selected as the research object, and 200 patients with duodenal ulcer were divided into two groups by "computer random method", the observation group was treated with omeprazole combined with famotidine, while the control group was treated with omeprazole, the therapeutic effect,the improvement time of symptoms and the level of gastrointestinal hormones in the two groups were analyzed.Results The total effective rate of duodenal ulcer patients in the observation group was 96.00% higher than that in the control group, there was a significant difference between the two groups, P0.05. The time of ulcer pain disappearance,heartburn disappearance and acid regurgitation disappearance in the observation group were shorter than those in the control group(P0.05). The AM(41.94±1.74)pg.mL-1、GAS(61.20±1.73)pg.mL-1 in the observation group were lower than those in the control group, CGRP(16.70±1.29)pg.mL-1、SS(13.99±1.23)pg.mL-1 in the observation group were higher than those in the control group, the difference was statistically significant(P 0.05). Conclusion Omeprazole combined with famotidine is effective and safe in the treatment of duodenal ulcer.
【CateGory Index】： R573.1