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《CHINESE JOURNAL OF CERIATRICS》 1996-04
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An analysis of 57 cases of multiple primary malignancy in the aged

Wang Yao;Zhao Wing; Chen Manli(Beijing Hospital,Beijing 100730)  
Objective To have a better understanding of the clinical and pathological features of multiple primary malignancy in the aged with respect to its occurrence, age of disease onset, predilecting sites , and time intermitting between the two malignancies. Methods The clinical and pathological data of 57 aged patients with multiple primary malignancy were studied. Forty-five patients had two, 10 had three and two had four primary malignant tumors. Results Forty-six of the 57 cases accounted for 15. 7% of the aged patients with malignancy hospitalized in the same period. The age of disease onset was between 60 and 80. The four predilecting sites were lung, colon, prostate and stomach.Sixteen patients had tumors in the same organ or paired organs. Fifteen patients had synchronous and 42 asynchronous multiple primary malignant tumors. The average time intermitting between two tumors was 7 years and 4 months. Forty three of the 57 patients died during the course of follow up and the autopsy rate was 88. 4%. Conclusions There is an increasing tendency of occurrence of multiple primary malignancy in the aged, especially in hospital with high autopsy rate. Early operation with supportive therapy is required for the aged with multiple primary malignancy if the general condition of the patient allows.
【CateGory Index】: R730.2
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