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《Chinese Journal of Physical Medicine and Retabulitation》 2002-04
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Experimental study of the effect of He-Ne laser irradiation on injured brain injuries in rats

WANG Tong,WANG Hongxing,LI Susu,LU Xiao, WANG Peipei, HOU Hong, SONG Fan.Department of Rehabilitation Medicine, The First Affi liated Hospital of Nanjing Medical University,Nanjing 210029,China  
Objective To evaluate the effect of low energy He Ne laser irradiation on the injuried brain tissues in rats. Methods Models of brain injury were made with sixty six Wistar rats which were randomly allocated into 6 groups(A F). The brain tissues of the rats in groups A to C received the He Ne laser irradiation for 1, 3 and 5 min, respectively, and were observed immediately after the irradiation, while the rats in groups E and F observed one week later, the rats in group D served as control. Results There was no significant difference with morphological changes and plasma level of SOD among the rats in groups A to C and those in groups D, but the plasma level of MDA in groups A to C was significantly lower than that in group D ( P 0.001). After laser treatment, the plasma level of MDA was obviously lower than that of group D ( P =0.001), while the level of plasma SOD was significantly increased ( P =0.001). The MDA level in the laser irradiated brain tissues was also lower than that in the control group( P =0.001). Conclusion He Ne laser irradiation can reduce the MDA level both in the plasma and injuried brain tissues, and increase the activity of SOD in plasma.
【CateGory Index】: R651.15
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