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《Chinese Journal of Physical Medicine》 1998-03
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Effect of Microwave Tissue Coagulation on the Anti tumor Immunity of Advanced Hepatoma Patients

Guan Jun,Yao Xiaoping,Wu Mengchao,et al.East Institute of Hepatobiliary Surgery,Shanghai200433  
Objective To investigate the effect of microwave tissue coagulation(MTC) on the anti-tumor immunity of patients with advanced unresectable hepatoma.Methods Patients were divided into three groups:MTC group(n=9),resection group(n=12),transarterial embolization(TAE) group(n=11).NK activity,LAK activity and T lymphocytes subsets were examined in all patients before and after the treatment respectively.Results The longest survival in MTC group was 22 months during follow up.NK activity,LAK activity and CD 3 percentage increased significantly(P 0.01 ) after MTC treatment,which were not seen after resection and TAE(P 0.05 ).Conclusion Indwelling hepatoma after MTC treatment could activize the anti tumor immunity of the patients.The mechanisms and the role of the effect need further study.
【CateGory Index】: R735.7
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