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Compliance in schizophrenic maintenance treatment

Jiang Kaida *, Li Shuchun, Luo Xingguang, et al. *Department of Psychiatry, Shanghai Medical University, Shanghai 200032  
To study the compliance of schizophrenic patients in maintenance treatment, 397 out patients was assessed with face to face interview. The results showed that 299 patients (75.3%) were of full compliance, and 98 cases (24.7%) were of partial compliance or non compliance. The patients aged over 30 years had a better compliance than those younger than 30 ( P 0.01). The cases with better interpersonal relationship within family had a better compliance than those with a worse one ( P 0.01) and those with severer current psychiatric symptoms, with maintenance dosage higher than 300 mg/d (equivalent to chlorpromazine), and with a higher score in Morning Side Recovery Status Scale had a worse compliance. Stepwise multifactorial regression analysis revealed the major factors related to compliance were as follows: interpersonal relationship within family, maintenance antipsychotic dosage, duration of maintenance treatment and scores in chronic schizophrenics standardized psychiatric symptom scale. The results indicate that enhance of compliance may decrease the relapse in patients with schizophrenia.
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